Description

7-Chloro-3,4-Dihydro-2,4-Dioxo-1(2H)-Quinazolineaceticacidethylester is a high-purity, synthetically derived quinazoline derivative, serving as a critical advanced pharmaceutical intermediate. Its core value lies in enabling the synthesis of complex active pharmaceutical ingredients (APIs) with precise molecular architecture. This compound is essential for research and development laboratories and production facilities focused on creating novel therapeutic agents, particularly in oncology and other specialized pharmaceutical sectors.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of complex drug molecules and active pharmaceutical ingredients (APIs).
• Oncology Drug Research: Used in the development and production of targeted cancer therapies and chemotherapeutic agents.
• Chemical Synthesis: Serves as a versatile precursor for creating other quinazoline-based compounds and heterocyclic libraries for screening.
• Biochemical Research: Employed in academic and industrial R&D for studying enzyme inhibition and signal transduction pathways.
• Process Development: Utilized in scaling up synthetic routes from laboratory to pilot and commercial manufacturing scales.

Basic Information

Product Name	7-Chloro-3,4-Dihydro-2,4-Dioxo-1(2H)-Quinazolineaceticacidethylester
CAS No.	112733-45-6
Molecular Formula	C₁₂H₁₁ClN₂O₄
Molecular Weight	282.68 g/mol
Synonyms	Ethyl 7-Chloro-2,4-dioxo-1,2,3,4-tetrahydroquinazoline-1-acetate; 1-Acetic acid, 7-chloro-3,4-dihydro-2,4-dioxo-1(2H)-quinazoline-, ethyl ester; 7-Chloro-1,2,3,4-tetrahydro-2,4-dioxoquinazoline-1-acetic acid ethyl ester; Ethyl (7-chloro-2,4-dioxo-1,2,3,4-tetrahydroquinazolin-1-yl)acetate; Quinazoline-1-acetic acid, 7-chloro-3,4-dihydro-2,4-dioxo-, ethyl ester
EINECS	Contact for details

Quality Control

Every batch of our 7-Chloro-3,4-Dihydro-2,4-Dioxo-1(2H)-Quinazolineaceticacidethylester is manufactured under strict quality management systems and undergoes rigorous analytical testing to ensure it meets the high-purity standards required for pharmaceutical synthesis. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our quality commitment aligns with cGMP principles for advanced intermediates, ensuring reliable supply and batch-to-batch consistency for your critical processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.