Description

Neuropeptide Y (20-36) is a specific C-terminal fragment of the full-length Neuropeptide Y (NPY) hormone, a key regulator in the central and peripheral nervous systems. This peptide sequence is crucial for research into receptor subtype specificity and the physiological roles of NPY, particularly in areas such as appetite regulation, anxiety, and cardiovascular function. It serves as an essential biochemical tool for neuroscientists, pharmacologists, and medicinal chemists engaged in neuropeptide research, drug discovery, and biochemical assay development.

Application

• Neuroscience Research: Used as a reference standard and active agent in studies of NPY receptor binding, signaling pathways, and neuronal communication.
• Pharmacological Studies: Employed to investigate the structure-activity relationship (SAR) of NPY fragments and to develop receptor-specific agonists or antagonists.
• Biochemical Assay Development: Serves as a critical component in ELISA, RIA, and other immunoassays for the quantification and detection of NPY-related activity.
• Metabolic Disorder Research: Applied in models studying NPY's role in energy homeostasis, food intake, and obesity.
• Cardiovascular Research: Utilized to explore the effects of NPY on blood pressure regulation and vascular tone.
• Academic & Institutional Research: A key reagent for university and pharmaceutical R&D laboratories focusing on peptide biology and neuroendocrinology.

Basic Information

Product Name	Neuropeptide Y (20-36)
CAS No.	112602-67-2
Molecular Formula	C89H137N27O24S
Molecular Weight	2021.3 g/mol
Synonyms	NPY (20-36); Neuropeptide Y Fragment 20-36; Tyr-Ile-Asn-Leu-Ile-Tyr-Arg-Leu-Arg-His-Tyr-Ile-Asn-Leu-Ile-Thr-Arg-Gln-Arg-Tyr-NH2; H-Tyr-Ile-Asn-Leu-Ile-Tyr-Arg-Leu-Arg-His-Tyr-Ile-Asn-Leu-Ile-Thr-Arg-Gln-Arg-Tyr-NH2; NPY 20-36 amide; [Tyr20, Tyr36]-Neuropeptide Y (20-36) amide
EINECS	Contact for details

Quality Control

Every batch of our Neuropeptide Y (20-36) is synthesized and purified under stringent conditions to ensure the highest standards of identity, purity, and biological activity. Our products undergo rigorous quality testing, including HPLC, MS, and amino acid analysis, to ensure compliance with research-grade specifications. Certificates of Analysis (COA) with detailed chromatographic and spectroscopic data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store desiccated at -20°C or below. This product is hygroscopic (moisture-sensitive). For long-term storage, it is recommended to keep the peptide lyophilized in a freezer. Allow the vial to equilibrate to room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (MS)	Consistent with theoretical molecular weight
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by weight)
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.