Description

H-Pro-β-Ala-Oh CAS NO 112558-45-9 is a high-purity, protected dipeptide building block widely used in advanced pharmaceutical research and peptide synthesis. Its primary value lies in providing a crucial, chemically defined intermediate for constructing complex peptide chains with specific structural and functional properties. This compound is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and life sciences sectors, particularly those developing novel therapeutic peptides and peptidomimetics.

Application

• Pharmaceutical Intermediate: A key building block in the solid-phase and solution-phase synthesis of therapeutic peptides.
• Peptidomimetic Research: Used to create modified peptide structures with enhanced stability, bioavailability, or biological activity.
• Bioconjugation: Serves as a spacer or linker molecule in the conjugation of peptides to other biomolecules, drugs, or surfaces.
• Chemical Biology Probes: Integral for synthesizing labeled or tagged peptides used in biochemical assays and diagnostic development.
• Academic & Industrial R&D: Employed in research laboratories for investigating peptide structure-activity relationships (SAR).
• API Development: A critical raw material in the development and scale-up of Active Pharmaceutical Ingredients (APIs) for peptide-based drugs.

Basic Information

Product Name	H-Pro-β-Ala-Oh
CAS No.	112558-45-9
Molecular Formula	C8H14N2O3
Molecular Weight	186.21 g/mol
Synonyms	L-Prolyl-β-alanine; Pro-β-Ala-OH; H-Pro-β-Ala-OH; (S)-1-(2-((3-Aminopropanoyl)amino)pyrrolidine-1-carbonyl)ethan-1-aminium; N-(3-Aminopropanoyl)-L-proline; L-Proline, N-(3-aminopropanoyl)-; β-Alanyl-L-proline; Protected Dipeptide Pro-βAla
EINECS	Contact for details

Quality Control

Our H-Pro-β-Ala-Oh is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation via spectroscopic methods, to ensure it meets the stringent requirements for pharmaceutical research and development. Certificates of Analysis (COA) with detailed batch-specific data are provided to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can affect stability and performance.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Total)	≥ 99.0%
Chiral Purity	≥ 99.0% (L-isomer)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.