Description

L-Glutamic Acid 5-Cyclohexyl Ester is a specialized amino acid derivative where the γ-carboxyl group of L-glutamic acid is esterified with cyclohexanol. This modification enhances its lipophilicity and alters its biochemical properties, making it a valuable intermediate for advanced research and synthesis. It is primarily utilized in the development of novel pharmaceutical compounds, particularly in peptide chemistry and as a building block for prodrugs and enzyme inhibitors. This high-purity chemical is essential for R&D laboratories and fine chemical manufacturers focused on creating targeted bioactive molecules.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of peptide-based drugs and prodrugs designed for improved bioavailability and targeted delivery.
• Biochemical Research: Used in enzymatic studies and as a substrate analog to investigate the function of glutamic acid-specific enzymes and receptors.
• Peptide Synthesis: Serves as a protected or modified glutamic acid residue in solid-phase and solution-phase peptide synthesis to introduce specific functional groups.
• Prodrug Development: Employed to create ester prodrugs of active pharmaceutical ingredients (APIs) to enhance membrane permeability and stability.
• Fine Chemical Synthesis: Acts as a chiral synthon for the asymmetric synthesis of complex organic molecules and natural product analogs.

Basic Information

Product Name	L-Glutamic Acid 5-Cyclohexyl Ester
CAS No.	112471-82-6
Molecular Formula	C11H19NO4
Molecular Weight	229.27 g/mol
Synonyms	L-Glutamic acid γ-cyclohexyl ester; (S)-2-Amino-5-(cyclohexyloxy)-5-oxopentanoic acid; Cyclohexyl L-glutamate; γ-Cyclohexyl L-glutamate; 5-Cyclohexyl L-glutamate; Glutamic acid 5-cyclohexyl ester; L-Glutamic acid 5-cyclohexyl ester; (S)-5-(Cyclohexyloxy)-4-carboxy-5-oxopentan-1-aminium
EINECS	Contact for details

Quality Control

Our L-Glutamic Acid 5-Cyclohexyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification and impurity profiling, to ensure it meets the high standards required for pharmaceutical research and fine chemical synthesis. A Certificate of Analysis (COA) detailing specific results for identity, assay, and purity is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Optical Rotation	[α]20/D: Specific range provided on COA
Chiral Purity (HPLC)	≥ 99.0% (L-isomer)
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.