Description

Hemoglobin F-Oakland is a specific variant of fetal hemoglobin, a critical protein for oxygen transport, identified by the CAS registry number 112444-77-6. This compound is of significant value in biochemical research and diagnostic development due to its unique structural properties that differentiate it from normal adult and fetal hemoglobins. It is primarily needed by researchers and manufacturers in the fields of hematology, clinical diagnostics, and biopharmaceutical development for studying hemoglobinopathies and creating specialized assays.

Application

• Biochemical Research Standard: Used as a reference material in studies of hemoglobin structure, function, and genetic mutations.
• Diagnostic Kit Development: Serves as a key component in the calibration and validation of diagnostic tests for sickle cell disease and thalassemias.
• Hematology Studies: Essential for in-vitro research into fetal hemoglobin expression and its role in mitigating certain blood disorders.
• Pharmaceutical R&D: Employed in drug discovery programs targeting the modulation of hemoglobin synthesis for therapeutic purposes.
• Quality Control Reagent: Acts as a control substance in laboratories ensuring the accuracy of chromatographic and electrophoretic separation techniques for hemoglobins.
• Educational Reference: Used in academic settings for teaching advanced concepts in protein chemistry and molecular biology.

Basic Information

Product Name	Hemoglobin F-Oakland
CAS No.	112444-77-6
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Hb F-Oakland; Fetal Hemoglobin Oakland; Hemoglobin F Oakland variant; γ-Globin Oakland; HbF Oakland; Gly->Asp substitution at γ-136; Hemoglobin variant F-Oakland
EINECS	Contact for details

Quality Control

Our Hemoglobin F-Oakland is produced and handled under stringent quality protocols. Each batch undergoes comprehensive analytical testing, including purity assessment by HPLC and identity confirmation via spectroscopic methods, to ensure it meets the exacting standards required for research and diagnostic applications. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C. This material is hygroscopic (moisture-sensitive) and should be handled in a controlled, dry environment to maintain stability. For long-term storage, consider keeping the product desiccated at -20°C.

Specification

Item	Specification
Appearance	Lyophilized powder
Identification (IR)	Conforms to standard
Purity (HPLC)	≥ 95%
Protein Content (Biuret)	≥ 90%
Moisture (Karl Fischer)	≤ 5.0%
Solubility	Clear solution in buffer

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.