Description

Phenylalanyl-Glycyl-Valyl-Statyl-Alanyl-Phenylalanine Methyl Ester is a synthetic peptide derivative of significant interest in advanced pharmaceutical research and development. This compound serves as a crucial intermediate or reference standard in the synthesis and study of novel protease inhibitors and other therapeutic agents. It is primarily utilized by research institutions, pharmaceutical companies, and biotechnology firms engaged in drug discovery programs targeting specific enzymatic pathways. The high-purity material is essential for ensuring the accuracy and reproducibility of experimental results in preclinical studies.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of complex peptide-based drug candidates, particularly protease inhibitors.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic assays to study protease activity and mechanism of action.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in peptide analysis via HPLC and LC-MS.
• Drug Discovery: Integral component in medicinal chemistry programs for structure-activity relationship (SAR) studies and lead optimization.
• Academic Research: Employed in university and institutional labs for fundamental studies in peptide chemistry and enzymology.

Basic Information

Product Name	Phenylalanyl-Glycyl-Valyl-Statyl-Alanyl-Phenylalanine Methyl Ester
CAS No.	112317-46-1
Molecular Formula	C38H53N7O8
Molecular Weight	735.87 g/mol
Synonyms	Phe-Gly-Val-Sta-Ala-Phe-OMe; H-Phe-Gly-Val-Sta-Ala-Phe-OMe; (S)-N-((S)-1-(((S)-1-(((S)-4-(((S)-1-Carboxy-3-phenylpropyl)amino)-3-hydroxy-1-oxobutan-2-yl)amino)-3-methyl-1-oxobutan-2-yl)amino)-1-oxo-3-phenylpropan-2-yl)glycyl-L-phenylalanine methyl ester; Statine-containing hexapeptide methyl ester; Protease inhibitor peptide fragment; CAS 112317-46-1
EINECS	Contact for details

Quality Control

Our Phenylalanyl-Glycyl-Valyl-Statyl-Alanyl-Phenylalanine Methyl Ester is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity, suitable for research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP guidelines for the production of advanced pharmaceutical intermediates, ensuring traceability and documentation for regulatory compliance.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive) and light-sensitive (store away from light). For long-term storage, keep desiccated under an inert atmosphere. Allow the sealed container to reach room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Purity (HPLC)	≥ 98.0%
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.