Description

4-Bromo-2,5-Difluoroaniline is a versatile halogenated aniline derivative that serves as a critical building block in advanced organic synthesis. Its unique combination of bromine and fluorine substituents on the aromatic ring makes it a highly valuable intermediate for creating complex molecules with tailored electronic and steric properties. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to develop active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring halogenated aromatic cores.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides, where the difluoro and bromo groups contribute to biological activity and metabolic stability.
• Liquid Crystal & OLED Materials: Serves as a building block for electron-transport materials and charge-transport layers in electronic displays and lighting.
• Polymer & Dye Chemistry: Employed in the production of specialty polymers, high-performance dyes, and pigments.
• Cross-Coupling Reactions: Acts as a substrate in Suzuki, Buchwald-Hartwig, and other palladium-catalyzed cross-coupling reactions to form complex biaryl structures.
• Research & Development: A valuable reagent for academic and industrial R&D in medicinal chemistry and material science.

Basic Information

Item	Details
Product Name	4-Bromo-2,5-Difluoroaniline
CAS No.	112279-60-4
Molecular Formula	C6H4BrF2N
Molecular Weight	208.00 g/mol
Synonyms	2,5-Difluoro-4-bromoaniline; 4-Bromo-2,5-difluorobenzenamine; 1-Amino-4-bromo-2,5-difluorobenzene; Benzenamine, 4-bromo-2,5-difluoro-; 4-Bromo-2,5-difluoro-phenylamine; 4-Br-2,5-F2-C6H2-NH2; 2,5-Difluoro-4-bromo-aniline
EINECS	Contact for details

Quality Control

Our 4-Bromo-2,5-Difluoroaniline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). This material is light-sensitive (store away from light) and should be kept under an inert atmosphere for long-term storage to prevent oxidation.

Specification

Item	Specification
Appearance	White to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.