Description

(R)-5-Amino-2-(((Benzyloxy)Carbonyl)Amino)Pentanoic Acid is a high-purity, non-proteinogenic amino acid derivative featuring a chiral center and a protected amine group. This compound is a critical chiral building block and intermediate in the synthesis of complex pharmaceutical molecules, particularly peptides and peptidomimetics. It is essential for research and development chemists in the pharmaceutical, biotechnology, and fine chemical sectors who require enantiomerically pure intermediates for drug discovery and process development. The compound, identified by CAS number 112229-51-3, is supplied under strict quality control to ensure batch-to-batch consistency for sensitive synthetic applications.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), especially those with peptide-like structures.
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis to incorporate a specific, protected ornithine-like residue into peptide chains.
• Protease Inhibitor Development: Serves as a core structural component in the research and development of enzyme inhibitors targeting various proteases.
• Chemical Biology & Probe Design: Utilized in the creation of labeled or modified amino acids for studying biological pathways and protein interactions.
• Asymmetric Synthesis: Acts as a starting material or auxiliary in asymmetric catalytic reactions to construct complex chiral molecules.
• Reference Standard: Provides a high-purity standard for analytical method development and quality control in pharmaceutical manufacturing.

Basic Information

Product Name	(R)-5-Amino-2-(((Benzyloxy)Carbonyl)Amino)Pentanoic Acid
CAS No.	112229-51-3
Molecular Formula	C14H20N2O4
Molecular Weight	280.32 g/mol
Synonyms	(R)-2-((((Benzyloxy)carbonyl)amino)-5-aminopentanoic acid; (R)-N2-Cbz-Ornithine; (R)-N2-Carbobenzyloxy-ornithine; (R)-Nα-Cbz-Ornithine; (R)-5-Amino-2-(((benzyloxy)carbonyl)amino)pentanoic acid; D-N2-Cbz-Ornithine; (R)-Ornithine, N2-[(phenylmethoxy)carbonyl]-; Z-D-Orn-OH
EINECS	Contact for details

Quality Control

Our (R)-5-Amino-2-(((Benzyloxy)Carbonyl)Amino)Pentanoic Acid is manufactured under a quality management system and undergoes rigorous analytical testing to ensure it meets the high standards required for pharmaceutical R&D. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, chiral purity, and impurity profiles. We can supply material compliant with current research and cGMP standards for non-clinical development stages. Certificates of Analysis (COA) are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C for long-term stability. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to prevent degradation. Allow the sealed container to reach room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.