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Palmitoyl-Cys((Rs)-2,3-Di(Palmitoyloxy)-Propyl)-Ser-Lys-Lys-Lys-Lys-Oh CAS NO 112208-00-1
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CAS No.:112208-00-1
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
Palmitoyl-Cys((Rs)-2,3-Di(Palmitoyloxy)-Propyl)-Ser-Lys-Lys-Lys-Lys-Oh is a synthetic lipopeptide derivative, widely recognized as a potent immunostimulant and vaccine adjuvant. Its core value proposition lies in its ability to enhance and modulate immune responses by mimicking bacterial membrane components, making it a critical tool in advanced therapeutic development. This compound is essential for researchers and manufacturers in the pharmaceutical and biotechnology sectors, particularly those focused on novel vaccine formulations, cancer immunotherapy, and targeted drug delivery systems.
Application
- Vaccine Adjuvant Development: A key component in subunit and peptide-based vaccines to enhance immunogenicity and efficacy.
- Cancer Immunotherapy: Used in experimental therapies to stimulate anti-tumor immune responses and improve the delivery of tumor-associated antigens.
- Liposomal and Nanoparticle Formulations: Serves as a functional lipid anchor to improve the stability and cellular uptake of nanocarriers for targeted drug delivery.
- Immunology Research: A standard tool for studying Toll-like receptor 2 (TLR2) signaling pathways and innate immune activation.
- Antiviral and Antibacterial Vaccine Platforms: Incorporated into vaccine candidates against infectious diseases to boost protective immunity.
- Peptide-Based Drug Conjugates: Utilized to modify peptides, enhancing their membrane permeability and pharmacokinetic profile.
Basic Information
| Item | Details |
|---|---|
| Product Name | Palmitoyl-Cys((Rs)-2,3-Di(Palmitoyloxy)-Propyl)-Ser-Lys-Lys-Lys-Lys-Oh |
| CAS No. | 112208-00-1 |
| Molecular Formula | C99H185N9O14S |
| Molecular Weight | Contact for details |
| Synonyms | Pam3Cys-Ser-(Lys)4; Pam3Cys-SKKKK; S-[2,3-Bis(palmitoyloxy)propyl]-N-palmitoyl-L-cysteinyl-L-seryl-tetra-L-lysine; N-Palmitoyl-S-[2,3-bis(palmitoyloxy)propyl]-L-cysteinyl-L-seryl-tetra-L-lysine; TLR2 Agonist Pam3CSK4; Synthetic Lipopeptide; Tripalmitoyl-S-glyceryl Cysteinyl-Serine-Lysine4; Immunostimulant Lipopeptide |
| EINECS | Contact for details |
Quality Control
Our Palmitoyl-Cys((Rs)-2,3-Di(Palmitoyloxy)-Propyl)-Ser-Lys-Lys-Lys-Lys-Oh is produced under stringent quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure compliance with research and development standards. Comprehensive Certificates of Analysis (COA) detailing purity, related substances, and other critical parameters are available upon request to support your regulatory and quality assurance needs.
Storage
Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive) and light-sensitive; prolonged exposure to air, moisture, or light should be avoided to maintain stability and potency. Allow the vial to equilibrate to room temperature before opening to prevent condensation.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white powder |
| Identification (HPLC/MS) | Conforms to reference standard |
| Purity (HPLC) | ≥ 95.0% |
| Water Content (KF) | ≤ 5.0% |
| Heavy Metals | ≤ 20 ppm |
| Residual Solvents (GC) | Meets ICH guidelines |
| Bacterial Endotoxins | < 10 EU/mg |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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