Description

5-Bromo-2-Fluorophenol is a halogenated phenol derivative that serves as a versatile and critical building block in advanced organic synthesis. Its unique structure, featuring both bromine and fluorine substituents on the aromatic ring, makes it a valuable intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing active ingredients and novel materials.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds targeting central nervous system disorders and infectious diseases.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides, where the bromo and fluoro groups enhance biological activity and stability.
• Liquid Crystal & OLED Materials: Serves as a precursor in the production of fluorine-containing liquid crystals and organic light-emitting diode (OLED) materials for electronic displays.
• Polymer Chemistry: Acts as a monomer or modifier in the synthesis of specialty polymers, including high-performance engineering plastics and resins.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to create biaryl structures.
• Chemical Research & Development: Employed in academic and industrial R&D labs for exploring new synthetic methodologies and creating compound libraries for screening.

Basic Information

Product Name	5-Bromo-2-Fluorophenol
CAS No.	112204-58-7
Molecular Formula	C6H4BrFO
Molecular Weight	191.00 g/mol
Synonyms	2-Fluoro-5-bromophenol; 5-Bromo-2-fluorophenol; 2-Fluoro-5-hydroxybromobenzene; Phenol, 5-bromo-2-fluoro-; 5-Bromo-2-fluoro-1-hydroxybenzene; 1-Bromo-4-fluoro-2-hydroxybenzene; 5-Bromo-2-fluorophenol (technical grade)
EINECS	Contact for details

Quality Control

Our 5-Bromo-2-Fluorophenol is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, supporting its use in regulated synthesis pathways.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its phenolic nature, ensure it is stored separately from strong oxidizing agents and bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	48 - 52 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.