Description

Prepro-Atrial Natriuretic Factor (56-92) (Human) is a defined synthetic peptide fragment corresponding to residues 56-92 of the human prepro-ANP (Atrial Natriuretic Peptide) precursor. This high-purity peptide is a critical research tool for investigating the biosynthesis, processing, and biological activity of ANP, a key hormone in cardiovascular and renal physiology. It is primarily utilized by pharmaceutical R&D teams, academic researchers, and diagnostic developers focused on hypertension, heart failure, and fluid-electrolyte balance studies.

Application

• Biochemical Research: Used as a standard or reference compound in studies of ANP precursor processing and enzyme kinetics.
• Antibody Production & Immunoassay Development: Serves as a specific immunogen for generating antibodies or as a calibrator in ELISA and RIA for detecting ANP-related peptides.
• Cell Signaling & Receptor Studies: Employed to investigate the structure-activity relationships and signaling pathways of natriuretic peptides in vitro.
• Pharmaceutical Screening: Acts as a key intermediate or reference material in drug discovery programs targeting natriuretic peptide pathways.
• Metabolic Pathway Analysis: Facilitates research into the proteolytic cleavage events that generate active ANP from its precursor.

Basic Information

Product Name	Prepro-Atrial Natriuretic Factor (56-92) (Human)
CAS No.	112199-06-1
Molecular Formula	C152H246N46O43S2
Molecular Weight	~3480.0 g/mol
Synonyms	Prepro-ANP (56-92); Atrial Natriuretic Peptide Precursor (56-92); ANP (56-92); hANP (56-92); Cardionatrin (56-92); Atriopeptin Precursor Fragment; PreproANP Fragment 56-92; Human Atrial Natriuretic Factor Fragment 56-92
EINECS	Contact for details

Quality Control

Our Prepro-Atrial Natriuretic Factor (56-92) (Human) is manufactured under stringent conditions to ensure batch-to-batch consistency and high biological reliability. Each lot is subjected to comprehensive analytical testing, including HPLC for purity and mass spectrometry for identity confirmation. Certificates of Analysis (COA) detailing purity, peptide content, and analytical data are provided to support your research and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store desiccated at -20°C or below. This product is hygroscopic (moisture-sensitive). For long-term storage, consider aliquoting to minimize freeze-thaw cycles and maintain stability.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by weight)
Amino Acid Analysis	Within ±10% of theoretical
Water Content (KF)	≤ 5.0%
Acetate Content (HPIC)	≤ 10.0%
Solubility	Soluble in water or dilute acetic acid

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.