Description

Angiogenin (108-122) is a synthetic peptide fragment corresponding to amino acids 108-122 of the full-length angiogenin protein. This bioactive peptide sequence is of significant interest for its role in modulating angiogenesis-related pathways and cellular signaling. It is primarily utilized by researchers and developers in the life sciences sector for biochemical and pharmacological studies. The compound is supplied under stringent quality control to ensure batch-to-batch consistency for critical applications.

Application

• Biomedical Research: Used as a key reagent in studying the structure-activity relationship (SAR) of angiogenin and its role in angiogenesis and cell proliferation.
• Pharmaceutical Development: Serves as a reference standard or an intermediate in the development of novel therapeutics targeting cancer and ischemic diseases.
• Cell Biology Studies: Applied in in vitro assays to investigate its effects on endothelial cell migration, tubule formation, and signal transduction mechanisms.
• Biochemical Reagent: Functions as a substrate or inhibitor in enzymatic studies to elucidate angiogenin's ribonucleolytic activity and receptor interactions.
• Diagnostic Tool Development: Potential use in the development of immunoassays or biosensors for detecting angiogenin-related biomarkers.

Basic Information

Product Name	Angiogenin (108-122)
CAS No.	112173-49-6
Molecular Formula	C73H118N22O22S
Molecular Weight	1680.9 g/mol
Synonyms	Angiogenin Fragment 108-122; Human Angiogenin (108-122); ANG (108-122); H2N-Cys-Lys-Asn-Gly-Arg-Gln-Leu-Tyr-Ile-Phe-Lys-Pro-Pro-Arg-Tyr-OH; Angiogenin Peptide (108-122); Angiogenin-derived peptide; CAS 112173-49-6
EINECS	Contact for details

Quality Control

Every batch of Angiogenin (108-122) is manufactured and tested under a strict quality management system. Our products undergo rigorous analytical testing, including HPLC and MS, to ensure high purity and identity confirmation, meeting the exacting standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided with each shipment to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake. For long-term storage, keep desiccated at -20°C.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC & MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by weight)
Amino Acid Composition	Conforms to theoretical values (±10%)
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 5.0%
Acetate Content (HPIC)	≤ 10.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.