Description

Angiogenin (108-123) CAS NO 112173-48-5 is a defined synthetic peptide fragment corresponding to residues 108-123 of the full-length angiogenin protein. This peptide is a critical research tool for investigating the structure-activity relationships and biological functions of angiogenin, particularly its role in angiogenesis and cell proliferation. It is essential for researchers and developers in pharmaceutical R&D, biochemical research, and diagnostic assay development who require high-purity, well-characterized peptide reagents.

Application

• Biomedical Research: Used as a reference standard and active agent in studies of angiogenesis, tumor biology, and cellular signaling pathways.
• Antibody Production & Characterization: Serves as a specific antigen for generating and screening monoclonal or polyclonal antibodies against angiogenin.
• Drug Discovery & Screening: Employed in high-throughput screening (HTS) assays to identify potential inhibitors or modulators of angiogenin activity.
• Diagnostic Development: Utilized as a calibrator or control in the development of immunoassays (e.g., ELISA) for detecting angiogenin levels in biological samples.
• Structure-Function Studies: Critical for mapping functional domains and understanding the peptide regions responsible for angiogenin's ribonucleolytic and cell-binding activities.
• Cell Culture & In Vitro Models: Applied in cell-based assays to study its effects on endothelial cell migration, tube formation, and proliferation.

Basic Information

Product Name	Angiogenin (108-123)
CAS No.	112173-48-5
Molecular Formula	C73H118N22O23S
Molecular Weight	1639.9 g/mol
Synonyms	Angiogenin Fragment 108-123; Human Angiogenin (108-123); ANG (108-123); H2N-Cys-Lys-Asn-Gly-Arg-Gln-Leu-Tyr-Leu-Cys-Asn-Pro-Val-Arg-Gly-Phe-COOH; Angiogenin Peptide (108-123); RNASE5 (108-123); Angiogenin Active Site Peptide
EINECS	Contact for details

Quality Control

Every batch of Angiogenin (108-123) is manufactured and analyzed under strict quality management systems. We provide comprehensive analytical data to ensure identity, purity, and consistency for your research. Certificates of Analysis (COA) detailing purity (by HPLC), molecular weight confirmation (by MS), and peptide content are available upon request. Our quality commitment supports compliance with relevant standards for research-grade biochemicals.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. For long-term storage, consider lyophilized powder under inert atmosphere. The product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC & MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by weight)
Amino Acid Composition	Conforms to theoretical values (±10%)
Molecular Weight	1639.9 ± 1.0 Da (Monoisotopic)
Solubility	Soluble in water or aqueous buffers

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.