Description

Prepro-Atrial Natriuretic Factor (26-55) (Human) is a defined synthetic peptide fragment corresponding to a specific region of the human prepro-ANP precursor protein. This high-purity biochemical is critical for cardiovascular and renal research, serving as a precise tool for studying natriuretic peptide signaling, receptor binding, and metabolic pathways. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and diagnostic developers focused on hypertension, heart failure, and related biomarker discovery.

Application

• Biochemical Research: Used as a reference standard and active agent in studies of atrial natriuretic peptide (ANP) biosynthesis, processing, and biological activity.
• Receptor Binding Assays: Essential for competitive binding studies to characterize and quantify ANP receptor subtypes (NPR-A, NPR-C) in various tissues.
• Antibody Production & Immunoassay Development: Serves as a key immunogen for generating specific antibodies and as a calibrator in ELISA or RIA kits for detecting ANP-related peptides.
• Cell Signaling Studies: Applied in vitro to investigate the downstream effects of ANP fragment signaling on cyclic GMP production, vasodilation, and natriuresis.
• Pharmaceutical Screening: Utilized in high-throughput screening (HTS) platforms to identify and evaluate novel modulators of the natriuretic peptide system for drug discovery.
• Academic & Clinical Research: Supports fundamental and translational research into cardiovascular diseases, fluid balance, and endocrine regulation.

Basic Information

Product Name	Prepro-Atrial Natriuretic Factor (26-55) (Human)
CAS No.	112160-82-4
Molecular Formula	C142H230N44O41S2
Molecular Weight	3177.7 g/mol
Synonyms	PreproANP (26-55); Atrial Natriuretic Peptide Precursor (26-55); ANP (26-55); hANP (26-55); Cardionatrin (26-55); Atriopeptin (26-55); P12655; Human Atrial Natriuretic Factor fragment 26-55
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Each batch of Prepro-ANP (26-55) is characterized using advanced analytical techniques to guarantee identity, purity, and consistency. Certificates of Analysis (COA) detailing purity by HPLC, peptide content, amino acid analysis, and mass spectrometry data are available upon request. We adhere to quality management principles suitable for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a freezer. This product is hygroscopic (moisture-sensitive). Allow the vial to reach room temperature in a desiccator before opening to minimize moisture uptake. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (MS)	Molecular weight confirmed by Mass Spectrometry
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by weight)
Amino Acid Analysis	Within ± 10% of theoretical composition
Solubility	Soluble in water or dilute acetic acid

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.