Description

6-Chloro-N4-(1-Phenyl-Ethyl)-Pyrimidine-4,5-Diamine is a high-purity, advanced pharmaceutical intermediate characterized by its specific pyrimidine-diamine structure. This compound matters as a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs), where its defined stereochemistry and functional groups enable precise molecular construction. It is primarily needed by research institutions and manufacturers in the pharmaceutical and agrochemical industries for developing new therapeutic agents and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the development of new-generation herbicides and fungicides that target specific plant pathogens.
• Chemical Research & Development: Serves as a versatile scaffold for medicinal chemistry, enabling structure-activity relationship (SAR) studies.
• Fine Chemical Production: Employed in the multi-step synthesis of complex, high-value specialty chemicals.
• Academic Research: Utilized in university and institutional labs for studying heterocyclic chemistry and reaction mechanisms.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects under cGMP conditions.

Basic Information

Product Name	6-Chloro-N4-(1-Phenyl-Ethyl)-Pyrimidine-4,5-Diamine
CAS No.	112088-62-7
Molecular Formula	C12H13ClN4
Molecular Weight	248.71 g/mol
Synonyms	6-Chloro-N4-(1-phenylethyl)pyrimidine-4,5-diamine; 4,5-Pyrimidinediamine, 6-chloro-N4-(1-phenylethyl)-; 6-Chloro-N-(1-phenylethyl)pyrimidine-4,5-diamine; 1-(6-Chloro-4,5-diaminopyrimidin-4-yl)-1-phenylethane; (RS)-6-Chloro-N4-(1-phenylethyl)pyrimidine-4,5-diamine; 6-Chloro-N4-(α-methylbenzyl)pyrimidine-4,5-diamine; 6-Chloro-N4-(1-phenylethyl)-4,5-pyrimidinediamine
EINECS	Contact for details

Quality Control

Our 6-Chloro-N4-(1-Phenyl-Ethyl)-Pyrimidine-4,5-Diamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D and production. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, ensuring full traceability and compliance with your internal specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.