Description

6-Chloro-N*4*-(1-Phenyl-Ethyl)-Pyrimidine-4,5-Diamine is a high-purity, advanced pharmaceutical intermediate characterized by its specific pyrimidine-diamine structure. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs), offering a key building block for medicinal chemistry research and development. It is primarily utilized by R&D laboratories and production facilities in the pharmaceutical and agrochemical industries seeking reliable, high-quality intermediates for scale-up and manufacturing.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of novel drug candidates, particularly in oncology and antiviral research.
• Agrochemical Synthesis: Used in the development of new pesticides and herbicides, leveraging its heterocyclic core for biological activity.
• Chemical Research & Development: Acts as a versatile building block for organic synthesis and method development in academic and industrial labs.
• Material Science: Potential applications in the creation of specialty polymers and advanced functional materials.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.

Basic Information

Product Name	6-Chloro-N*4*-(1-Phenyl-Ethyl)-Pyrimidine-4,5-Diamine
CAS No.	112088-61-6
Molecular Formula	C12H13ClN4
Molecular Weight	248.71 g/mol
Synonyms	6-Chloro-4,5-diamino-N-(1-phenylethyl)pyrimidine; 4,5-Diamino-6-chloro-N-(1-phenylethyl)pyrimidine; 6-Chloro-N-(α-methylbenzyl)pyrimidine-4,5-diamine; 6-Chloro-N-(1-phenylethyl)-4,5-pyrimidinediamine; 112088-61-6; 6-Chloro-N4-(1-phenylethyl)pyrimidine-4,5-diamine; 6-Chloro-N-(1-phenylethyl)pyrimidine-4,5-diamine
EINECS	Contact for details

Quality Control

Our 6-Chloro-N*4*-(1-Phenyl-Ethyl)-Pyrimidine-4,5-Diamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specifications and test results. Our commitment to quality supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and incompatible materials. For long-term storage, consider an inert atmosphere to maintain product stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.