Description

9-Amino-n-Acetylneuraminic Acid is a chemically modified derivative of sialic acid, a critical carbohydrate found in glycoproteins and glycolipids. This compound serves as a key intermediate and building block in the synthesis of more complex sialic acid analogs and glycomimetics. It is essential for researchers and manufacturers in the pharmaceutical and biotechnology sectors, particularly those developing antiviral agents, diagnostic tools, and novel therapeutic glycoconjugates.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of neuraminidase inhibitors and other antiviral drug candidates targeting influenza and other viruses.
• Glycobiology Research: Used as a standard and building block for studying sialic acid metabolism, cell-cell recognition, and pathogen-host interactions.
• Diagnostic Reagent Development: Employed in the production of enzyme substrates and probes for detecting sialidase (neuraminidase) activity in clinical and research assays.
• Bioconjugation & Vaccine Development: Acts as a chemical handle for modifying proteins, lipids, or nanoparticles to create targeted vaccines and drug delivery systems.
• Enzymatic Synthesis: Serves as a substrate or inhibitor for enzymes like sialyltransferases and neuraminidases in biocatalytic processes.
• Chemical Biology Tool: Utilized to probe and modulate biological pathways involving sialic acid, aiding in the discovery of new therapeutic targets.

Basic Information

Product Name	9-Amino-n-Acetylneuraminic Acid
CAS No.	112037-47-5
Molecular Formula	C11H19NO9
Molecular Weight	309.27 g/mol
Synonyms	9-Amino-Neu5Ac; 9-Amino-5-acetamido-3,5-dideoxy-D-glycero-D-galacto-non-2-ulosonic Acid; 9-Amino-N-acetylneuraminic Acid; 9-Amino-sialic Acid; 9-Amino-NANA; 9-Amino-5-N-acetylneuraminic Acid; 9-Amino-NeuAc; 9-Amino-2-keto-5-acetamido-3,5-dideoxynononic Acid
EINECS	Contact for details

Quality Control

Our 9-Amino-n-Acetylneuraminic Acid is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (NMR, IR), to ensure it meets the high standards required for research and pharmaceutical applications. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.