Description

D-Aspartic Acid Diethyl Ester Hydrochloride is a high-purity, protected amino acid derivative essential for advanced organic synthesis. This compound serves as a critical chiral building block, enabling the controlled introduction of the D-aspartic acid moiety into complex molecular architectures. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors for applications including peptide synthesis and the development of active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and production of peptide-based drugs and other bioactive molecules.
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis to incorporate D-aspartic acid residues, which can influence peptide stability and biological activity.
• Biochemical Research: Serves as a standard or reagent in enzymatic studies and metabolic pathway investigations involving amino acid analogs.
• Fine Chemical Production: Employed in the synthesis of specialized chemicals, catalysts, and ligands for asymmetric synthesis.
• Academic & R&D: A valuable tool for chemists in universities and corporate R&D labs exploring new synthetic methodologies and compound libraries.

Basic Information

Product Name	D-Aspartic Acid Diethyl Ester Hydrochloride
CAS No.	112018-26-5
Molecular Formula	C8H16ClNO4
Molecular Weight	225.67 g/mol
Synonyms	D-Aspartic acid β-diethyl ester hydrochloride; (R)-2-Aminosuccinic acid 4-ethyl ester 1-ethyl ester hydrochloride; Diethyl D-aspartate hydrochloride; H-D-Asp(OEt)-OEt·HCl; (R)-Diethyl 2-aminosuccinate hydrochloride; D-Aspartic acid diethyl ester HCl; D-Asp(OEt)2·HCl
EINECS	Contact for details

Quality Control

Our D-Aspartic Acid Diethyl Ester Hydrochloride is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, detailing key parameters such as assay, chiral purity, and impurity profiles. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed immediately after use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.