Description

3-[(5-Bromopyrimidin-2-Yl)Oxy]Aniline is a high-purity, advanced pharmaceutical intermediate characterized by its bromopyrimidine and aniline functional groups. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in kinase inhibitor research and development. It is primarily required by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in creating targeted therapies for oncology and other disease areas.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of kinase inhibitors and other small molecule drug candidates.
• Chemical Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Agrochemical Synthesis: Serves as a precursor for developing novel crop protection agents and herbicides.
• Material Science: Potential monomer or functionalizing agent for creating specialty polymers with specific electronic or binding properties.

Basic Information

Product Name	3-[(5-Bromopyrimidin-2-Yl)Oxy]Aniline
CAS No.	111986-67-5
Molecular Formula	C10H8BrN3O
Molecular Weight	266.10 g/mol
Synonyms	3-[(5-Bromopyrimidin-2-yl)oxy]benzenamine; 3-Amino-1-(5-bromopyrimidin-2-yloxy)benzene; 1-(5-Bromopyrimidin-2-yloxy)-3-aminobenzene; 3-(5-Bromopyrimidin-2-yloxy)phenylamine; 2-(3-Aminophenoxy)-5-bromopyrimidine; 5-Bromo-2-(3-aminophenoxy)pyrimidine; Benzenamine, 3-[(5-bromopyrimidin-2-yl)oxy]-
EINECS	Contact for details

Quality Control

Our 3-[(5-Bromopyrimidin-2-Yl)Oxy]Aniline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This material is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.