Description

Abecarnil is a high-purity benzodiazepine receptor partial agonist, identified by CAS No. 111841-85-1. This compound is valued for its significant research and development applications in the field of neuropharmacology. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and fine chemical manufacturers focused on central nervous system (CNS) therapeutics.

Application

• Pharmaceutical Reference Standard: Serves as a certified reference material (CRM) for analytical method development, validation, and quality control in drug manufacturing.
• Neuroscience Research: Used as a critical tool compound in preclinical studies to investigate GABAA receptor pharmacology, anxiolytic mechanisms, and sedative-hypnotic pathways.
• Drug Discovery & Development: Acts as a key intermediate or active pharmaceutical ingredient (API) in the synthesis and development of novel anxiolytic and neuroprotective agents.
• Metabolite Studies: Employed in the identification and quantification of metabolites during pharmacokinetic and ADME (Absorption, Distribution, Metabolism, and Excretion) profiling.
• Biochemical Assays: Utilized in high-throughput screening (HTS) and in vitro receptor binding assays to evaluate compound libraries for CNS activity.

Basic Information

Product Name	Abecarnil
CAS No.	111841-85-1
Molecular Formula	C16H12N2O2
Molecular Weight	264.28 g/mol
Synonyms	Abecarnil; Isobutyl-6-benzyloxy-4-methoxymethyl-β-carboline-3-carboxylate; ZK 112119; β-Carboline, 6-(benzyloxy)-4-(methoxymethyl)-1-(2-methylpropyl)-, 3-carboxylate; 6-Benzyloxy-4-methoxymethyl-β-carboline-3-carboxylic acid isobutyl ester; 3-Isobutoxycarbonyl-6-benzyloxy-4-methoxymethyl-β-carboline
EINECS	Contact for details

Quality Control

Our Abecarnil is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, IR and NMR for structural confirmation, and residual solvent analysis. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, ensuring compliance with research and development grade standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 2.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.