Description

2-Bromo-3-Fluoroaniline is a halogenated aniline derivative that serves as a versatile and critical building block in advanced organic synthesis. Its unique structure, featuring both bromine and fluorine substituents on the aromatic ring, makes it an essential intermediate for introducing specific steric and electronic properties into target molecules. This compound is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical and agrochemical sectors for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring halogenated aromatic motifs.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides where the bromo-fluoroaniline scaffold contributes to biological activity.
• Material Science: Building block for advanced polymers, liquid crystals, and electronic materials that benefit from halogenated aromatic units.
• Dye and Pigment Manufacturing: Intermediate in the production of specialized dyes and pigments, leveraging the aniline functionality.
• Cross-Coupling Reactions: Serves as a substrate in palladium-catalyzed reactions like Suzuki, Buchwald-Hartwig, and Ullmann couplings for C-N and C-C bond formation.
• Chemical Research: Valuable reagent in academic and industrial R&D for exploring new synthetic methodologies and creating compound libraries.

Basic Information

Product Name	2-Bromo-3-Fluoroaniline
CAS No.	111721-75-6
Molecular Formula	C6H5BrFN
Molecular Weight	190.01 g/mol
Synonyms	2-Bromo-3-fluoroaniline; 3-Fluoro-2-bromoaniline; 1-Amino-2-bromo-3-fluorobenzene; 2-Bromo-3-fluoro-benzenamine; Benzenamine, 2-bromo-3-fluoro-; Aniline, 2-bromo-3-fluoro-; (2-Bromo-3-fluorophenyl)amine
EINECS	Contact for details

Quality Control

Our 2-Bromo-3-Fluoroaniline is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) for each lot, detailing key parameters such as assay, identity, and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, and we support our clients' needs for regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Light yellow to brown crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Melting Point	Contact for details
Water Content (KF)	≤0.5%
Related Substances (HPLC)	Total impurities ≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.