Description

α-Methyl-D-Lysine Hydrochloride is a high-purity, non-proteinogenic amino acid derivative of significant interest in pharmaceutical research and development. This chiral compound serves as a critical building block and a key reference standard in the synthesis of novel peptide-based therapeutics and enzyme inhibitors. It is primarily utilized by research institutions, pharmaceutical companies, and fine chemical manufacturers engaged in metabolic studies, proteomics, and the development of targeted drug candidates.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of peptide-based drugs and enzyme inhibitors.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies, particularly those involving lysine-specific enzymes and metabolic pathways.
• Proteomics & Metabolomics: Serves as a critical reference standard and analytical reagent for mass spectrometry and chromatography in biomarker discovery.
• Peptide Synthesis: Employed as a modified amino acid building block in solid-phase and solution-phase peptide synthesis to introduce specific structural or functional properties.
• Academic Research: Utilized in university and institutional labs for fundamental studies in organic chemistry, medicinal chemistry, and chemical biology.

Basic Information

Product Name	α-Methyl-D-Lysine Hydrochloride
CAS No.	111717-28-3
Molecular Formula	C7H16N2O2 • HCl
Molecular Weight	196.67 g/mol (Free base: 160.22 g/mol)
Synonyms	(2R)-2-Amino-6-amino-2-methylhexanoic acid hydrochloride; D-α-Methyllysine hydrochloride; (R)-2-Amino-2-methyl-6-aminohexanoic acid hydrochloride; H-D-α-MeLys-OH • HCl; (2R)-2-Methyl-2,6-diaminohexanoic acid hydrochloride; D-2-Amino-2-methyl-6-aminohexanoic acid hydrochloride
EINECS	Contact for details

Quality Control

Our α-Methyl-D-Lysine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure it meets the stringent requirements for research and pharmaceutical applications. A detailed Certificate of Analysis (COA) documenting identity, purity (HPLC), chiral purity, and related substances is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and purity. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% (D-isomer)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.