Description

D-Ornithine, 2-Ethynyl- (9Ci) is a specialized, non-proteinogenic amino acid derivative featuring an ethynyl modification at the 2-position of the D-ornithine backbone. This unique structure makes it a valuable advanced pharmaceutical intermediate and a versatile building block for organic synthesis, particularly in medicinal chemistry research. It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers developing novel therapeutic agents, enzyme inhibitors, and bioactive probes.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly enzyme inhibitors and mechanism-based inactivators.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and the development of targeted bioactive molecules due to its modified amino acid scaffold.
• Biochemical Tool Compound: Serves as a precursor or analog in the study of ornithine-related metabolic pathways and polyamine biosynthesis.
• Peptidomimetic Synthesis: Incorporated into peptide analogs to alter stability, bioavailability, or receptor binding properties.
• Organic Synthesis Building Block: The ethynyl group enables further chemical transformations via click chemistry (e.g., CuAAC) and other cross-coupling reactions.

Basic Information

Item	Details
Product Name	D-Ornithine, 2-Ethynyl- (9Ci)
CAS No.	111714-49-9
Molecular Formula	C7H12N2O2
Molecular Weight	156.18 g/mol
Synonyms	(2R)-2-Ethynyl-1,5-diaminopentanoic acid; (R)-2-Ethynylornithine; D-2-Ethynylornithine; 2-Ethynyl-D-ornithine; (R)-2-Ethynyl-1,5-diaminopentanoic acid; 2-Ethynyl-(R)-ornithine; UNII-Contact for details; (2R)-2-Ethynylornithine
EINECS	Contact for details

Quality Control

Our D-Ornithine, 2-Ethynyl- (9Ci) is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for all shipments. Specifications are designed to meet the stringent requirements of pharmaceutical R&D and advanced synthesis applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area. Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Optical Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.