Description

Elastin Polypentapeptide, Ile(1)- CAS NO 111583-50-7 is a synthetic polypeptide fragment that mimics the repeating pentapeptide sequence (Val-Pro-Gly-Val-Gly) found in natural elastin. This compound is of significant value for research and development in biomaterials and regenerative medicine due to its ability to self-assemble into coacervates and fibrillar structures under physiological conditions. It is primarily needed by researchers and product developers in the pharmaceutical, cosmetic, and advanced biomaterials industries for applications ranging from tissue engineering scaffolds to bioactive skincare formulations.

Application

• Biomedical Research: Fundamental studies on elastin assembly, protein-protein interactions, and extracellular matrix (ECM) mimicry.
• Tissue Engineering: As a key component in the development of synthetic, elastin-like scaffolds for vascular grafts, skin substitutes, and cartilage repair.
• Cosmetic & Skincare Actives: Incorporation into anti-aging and firming formulations to impart elasticity and improve skin texture.
• Drug Delivery Systems: Utilization in the design of stimuli-responsive carriers and hydrogels for controlled release applications.
• Bioink Formulation: As a bioactive polymer for 3D bioprinting to create complex, cell-laden tissue constructs.
• Surface Modification: Coating of medical devices and implants to enhance biocompatibility and reduce immune response.

Basic Information

Product Name	Elastin Polypentapeptide, Ile(1)- CAS NO 111583-50-7
CAS No.	111583-50-7
Molecular Formula	C22H36N6O7
Molecular Weight	496.56 g/mol
Synonyms	Ile-Pro-Gly-Val-Gly; Isoleucine-Proline-Glycine-Valine-Glycine; IPGVG; Elastin Pentapeptide; Poly(IPGVG); Elastin-like Polypeptide (ELP) fragment; Val-Pro-Gly-Val-Gly analog; (Ile1)-Elastin Polypentapeptide
EINECS	Contact for details

Quality Control

Our Elastin Polypentapeptide is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and MS for identity confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing purity, sequence verification, and endotoxin levels are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Amino Acid Analysis	Conforms to theoretical composition
Water Content (KF)	≤ 5.0 %
Peptide Content	≥ 80 %
Endotoxin	< 10 EU/mg

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.