Description

7-Glutaryl-Leucyl-Phenylalaninamide-4-Trifluoromethyl-2-Quinolinone is a specialized synthetic peptide derivative and heterocyclic compound designed for advanced research and development applications. This compound is valued for its unique molecular architecture, which combines a peptide backbone with a fluorinated quinolinone moiety, offering a versatile scaffold for biochemical studies. It is primarily utilized by researchers and process development scientists in the pharmaceutical and biotechnology sectors for investigating enzyme inhibition, receptor binding, and as a key intermediate in the synthesis of novel therapeutic agents.

Application

• Pharmaceutical Research: Serves as a critical intermediate or reference standard in the synthesis and development of novel drug candidates, particularly protease inhibitors.
• Biochemical Assays: Used as a substrate or inhibitor in enzymatic studies to elucidate biological pathways and mechanisms of action.
• Medicinal Chemistry: Acts as a core scaffold for structure-activity relationship (SAR) studies to optimize potency and selectivity of lead compounds.
• Peptide Chemistry: Employed in advanced peptide synthesis and modification research due to its glutaryl and phenylalaninamide groups.
• Fluorinated Compound Studies: The trifluoromethyl-quinolinone component makes it valuable for research into the effects of fluorination on bioavailability and metabolic stability.
• Academic & Institutional R&D: Used in university and research institute laboratories for fundamental chemical and biological research projects.

Basic Information

Product Name	7-Glutaryl-Leucyl-Phenylalaninamide-4-Trifluoromethyl-2-Quinolinone
CAS No.	111574-82-4
Molecular Formula	C30H35F3N4O6
Molecular Weight	604.62 g/mol
Synonyms	7-Glutaryl-L-leucyl-L-phenylalaninamide-4-(trifluoromethyl)-2(1H)-quinolinone; N2-[N-(N-L-Leucyl-L-phenylalanyl)]-L-glutamine 1-(4-Trifluoromethyl-2-oxo-1,2-dihydroquinolin-7-yl) ester; Glutaryl-Leu-Phe-NH2-TFMQ; TFQ-Peptide Conjugate; 4-Trifluoromethyl-2-quinolinone-7-carboxylic acid (glutaryl-leucyl-phenylalaninamide) ester
EINECS	Contact for details

Quality Control

Every batch of 7-Glutaryl-Leucyl-Phenylalaninamide-4-Trifluoromethyl-2-Quinolinone is manufactured under controlled conditions and undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our quality system is designed to meet the stringent requirements of research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity (typically by HPLC), identification (IR, NMR), and impurity profiles is provided with each shipment to support your critical work.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider desiccation or storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.