Description

Pentafluorophenyl Formate is a highly reactive and versatile fluorinated aryl ester building block. Its primary value lies in its role as an efficient acylating and formylating agent, particularly in the synthesis of complex organic molecules where the pentafluorophenyl group acts as an excellent leaving group. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors, enabling the development of active ingredients, specialty polymers, and high-performance chemical intermediates.

Application

• Pharmaceutical Intermediate: Key reagent in peptide coupling and amide bond formation for API synthesis.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and plant growth regulators.
• Polymer Chemistry: Serves as a monomer or cross-linking agent for synthesizing specialty fluorinated polymers with enhanced stability.
• Organic Synthesis Reagent: Employed as a formyl source or activating agent in multi-step synthetic routes for fine chemicals.
• Ligand and Catalyst Preparation: Useful in modifying ligands or creating metal-organic frameworks (MOFs) and catalysts.
• Bioconjugation Chemistry: Facilitates the labeling and modification of biomolecules for diagnostic and research applications.

Basic Information

Product Name	Pentafluorophenyl Formate
CAS No.	111333-97-2
Molecular Formula	C7HF5O2
Molecular Weight	212.08 g/mol
Synonyms	Formic Acid Pentafluorophenyl Ester; Pentafluorophenyl Formiate; PFP Formate; 2,3,4,5,6-Pentafluorophenyl Formate; Perfluorophenyl Formate; NSC 405124; C7HF5O2
EINECS	Contact for details

Quality Control

Our Pentafluorophenyl Formate is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and FTIR, to ensure high purity and batch-to-batch consistency. We provide detailed Certificates of Analysis (COA) with each shipment, documenting all critical quality attributes. Our production adheres to cGMP principles where applicable, supporting its use in regulated synthesis pathways.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials. Due to its light-sensitive nature, containers should be kept in opaque or amber glass under an inert atmosphere if long-term stability is required.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (by GC/HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.