Description

6-Chloro[1,2,4]Triazolo[4,3-b]pyridazine-3-thiol is a heterocyclic organic compound featuring a fused triazolopyridazine core, which serves as a versatile and high-value synthetic intermediate. This compound is critical for research and development in medicinal chemistry, where its unique scaffold is utilized to construct novel pharmacologically active molecules. It is primarily sought after by pharmaceutical R&D laboratories, agrochemical innovators, and advanced material scientists for the synthesis of new chemical entities.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, particularly in the development of kinase inhibitors, antiviral agents, and central nervous system (CNS) active compounds.
• Agrochemical Research: Used in the discovery and development of new herbicides, fungicides, and insecticides, leveraging its heterocyclic structure for bioactivity.
• Material Science Precursor: Serves as a starting material for creating specialized heterocyclic polymers, ligands for catalysis, or organic electronic materials.
• Chemical Biology Probe: Employed in the design and synthesis of molecular probes to study biological pathways and enzyme functions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds and small-scale API development.

Basic Information

Product Name	6-Chloro[1,2,4]triazolo[4,3-b]pyridazine-3-thiol
CAS No.	111317-12-5
Molecular Formula	C5H2ClN5S
Molecular Weight	199.62 g/mol
Synonyms	6-Chloro-3-mercapto-[1,2,4]triazolo[4,3-b]pyridazine; 6-Chloro-1,2,4-triazolo[4,3-b]pyridazine-3-thiol; 3H-[1,2,4]Triazolo[4,3-b]pyridazine-3-thione, 6-chloro-; 6-Chloro-3-thioxo-3,4-dihydro-[1,2,4]triazolo[4,3-b]pyridazine; 111317-12-5; 6-Chloro-1,2,4-triazolo[4,3-b]pyridazin-3-thiol
EINECS	Contact for details

Quality Control

Our 6-Chloro[1,2,4]triazolo[4,3-b]pyridazine-3-thiol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This material is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0% (Standard Grade)
Purity (HPLC)	≥ 98.0% / ≥ 99.0% (High Purity Grades Available)
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.