Description

1(2H)-Pyrimidinecarboxaldehyde, Tetrahydro-5-Hydroxy-3-Methyl- (9Ci) is a specialized heterocyclic building block of significant interest in advanced organic synthesis. This compound matters as a key chiral intermediate for constructing complex molecular architectures, particularly in the pharmaceutical sector. It is primarily needed by research and development chemists and process development teams in the fine chemical and pharmaceutical industries for the synthesis of novel active pharmaceutical ingredients (APIs) and other high-value compounds.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral synthon in the research and development of new therapeutic agents, particularly for central nervous system (CNS) and antiviral applications.
• Asymmetric Synthesis: Utilized as a building block in stereoselective reactions to introduce complex, functionalized pyrimidine motifs into target molecules.
• Agrochemical Research: Employed in the discovery and synthesis of novel crop protection agents and pesticides.
• Material Science Precursor: Investigated for the development of specialty polymers and organic electronic materials with unique properties.
• Academic & Contract Research: Used in university and CRO (Contract Research Organization) laboratories for methodological studies and the exploration of new chemical spaces.
• Process Chemistry Development: Acts as a starting material for scaling up synthetic routes under Good Manufacturing Practice (GMP) conditions for clinical trial material production.

Basic Information

Product Name	1(2H)-Pyrimidinecarboxaldehyde, Tetrahydro-5-Hydroxy-3-Methyl- (9Ci)
CAS No.	111280-65-0
Molecular Formula	C7H12N2O2
Molecular Weight	156.18 g/mol
Synonyms	5-Hydroxy-3-methyltetrahydro-1(2H)-pyrimidinecarboxaldehyde; 3-Methyl-5-hydroxy-tetrahydro-pyrimidine-1-carbaldehyde; Tetrahydro-5-hydroxy-3-methyl-1(2H)-pyrimidinecarboxaldehyde; 1(2H)-Pyrimidinecarboxaldehyde, tetrahydro-5-hydroxy-3-methyl-; 3-Methyl-5-hydroxytetrahydro-1(2H)-pyrimidinecarbaldehyde; 5-Hydroxy-3-methyl-1,2,3,4-tetrahydropyrimidine-1-carbaldehyde
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. We provide comprehensive analytical data to support your research and development needs. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request. Our quality systems are designed to meet the stringent requirements of pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This compound is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive); therefore, containers should be kept sealed under an inert atmosphere if specified.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.