Description

n-Decanoyl-D-Erythro-Sphingosine is a synthetic, high-purity sphingolipid derivative, specifically a C10 fatty acid-conjugated ceramide analog. This compound is a critical biochemical tool and building block for advanced research in lipidomics, cell signaling, and membrane biophysics. It is primarily utilized by research institutions and pharmaceutical developers focused on studying sphingolipid metabolism, apoptosis, and skin barrier function. The material is supplied to exacting standards to ensure reliable and reproducible experimental results.

Application

• Biochemical Research: A key standard and precursor for investigating sphingolipid biosynthesis, degradation pathways, and their role in cellular signaling cascades.
• Pharmaceutical Development: Used as an intermediate or reference compound in the discovery of novel therapeutics targeting metabolic disorders, cancer, and inflammatory diseases.
• Cosmeceutical Studies: Employed in vitro and ex vivo research to model and enhance skin barrier function and ceramide-based moisturization mechanisms.
• Lipidomics: Serves as a critical analytical standard for the identification and quantification of complex sphingolipids in mass spectrometry-based lipid profiling.
• Cell Biology: Used to study ceramide-mediated processes such as apoptosis, cell differentiation, and stress responses in various cell lines.
• Membrane Biophysics: Incorporated into artificial lipid bilayers and vesicles to study the biophysical properties and organization of sphingolipid-rich membrane domains (lipid rafts).

Basic Information

Product Name	n-Decanoyl-D-Erythro-Sphingosine
CAS No.	111122-57-7
Molecular Formula	C28H55NO4
Molecular Weight	469.75 g/mol
Synonyms	N-Decanoylsphingosine; D-erythro-C10-Ceramide; N-Caproyl-D-erythro-sphingosine; Ceramide C10; N-C10:0-Ceramide (d18:1/10:0); (2S,3R,4E)-2-Decanamido-4-octadecene-1,3-diol; N-Decanoyl-4-sphingenine; C10 Ceramide
EINECS	Contact for details

Quality Control

Our n-Decanoyl-D-Erythro-Sphingosine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical characterization, including HPLC for purity, NMR for structural confirmation, and mass spectrometry for identity verification. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to ensure traceability and consistency for your research and development needs.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture condensation. Keep the container in a dry, cool, and well-ventilated area.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 10 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.