Description

4,6-Dichloro-5-Iodo-2-Methylpyrimidine is a high-value halogenated pyrimidine building block essential for advanced organic synthesis. This compound matters for its role as a key intermediate in the development of active pharmaceutical ingredients (APIs) and agrochemicals, where its unique substitution pattern enables precise molecular modifications. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex heterocyclic scaffolds.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, particularly in antiviral and anticancer research.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and fungicides, leveraging its pyrimidine core.
• Chemical Research & Development: Serves as a versatile building block for creating libraries of compounds in medicinal chemistry and material science.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for metal-catalyzed cross-coupling reactions.
• Material Science Precursor: Potential use in the synthesis of organic electronic materials and photoactive compounds.

Basic Information

Product Name	4,6-Dichloro-5-Iodo-2-Methylpyrimidine
CAS No.	111079-21-1
Molecular Formula	C5H3Cl2IN2
Molecular Weight	288.90 g/mol
Synonyms	5-Iodo-4,6-dichloro-2-methylpyrimidine; 2-Methyl-4,6-dichloro-5-iodopyrimidine; 4,6-Dichloro-5-iodo-2-methyl-pyrimidine; 4,6-Dichloro-5-iodo-2-methyl-1,3-diazine; 111079-21-1; 4,6-Dichloro-5-iodo-2-methyl-1,3-diazine
EINECS	Contact for details

Quality Control

Our 4,6-Dichloro-5-Iodo-2-Methylpyrimidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging during storage and handling.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Residual Solvents (GC)	Complies with ICH guidelines
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.