Description

4-Chloro-5-Iodo-2-Methyl-Pyrimidine is a halogenated pyrimidine derivative serving as a versatile and critical building block in advanced organic synthesis. This compound is valued for its unique reactivity profile, enabling the construction of complex heterocyclic systems essential for pharmaceutical and agrochemical research. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for applications in drug discovery and material science.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for antiviral and anticancer drug candidates.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and plant growth regulators.
• Chemical Research & Development: Serves as a versatile scaffold for constructing complex heterocyclic libraries in medicinal chemistry and material science.
• Ligand & Catalyst Development: Employed in the preparation of specialized ligands for metal-catalyzed cross-coupling reactions.
• Nucleoside Analog Synthesis: A crucial building block for creating modified nucleosides with potential therapeutic activity.
• Material Science: Investigated for the development of organic electronic materials and photoactive compounds.

Basic Information

Product Name	4-Chloro-5-Iodo-2-Methyl-Pyrimidine
CAS No.	111079-17-5
Molecular Formula	C5H4ClIN2
Molecular Weight	254.46 g/mol
Synonyms	2-Methyl-4-chloro-5-iodopyrimidine; 5-Iodo-4-chloro-2-methylpyrimidine; 4-Chloro-5-iodo-2-methylpyrimidine; 2-Methyl-5-iodo-4-chloropyrimidine; 4-Chloro-2-methyl-5-iodopyrimidine; 5-Iodo-2-methyl-4-chloropyrimidine
EINECS	Contact for details

Quality Control

Our 4-Chloro-5-Iodo-2-Methyl-Pyrimidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing purity, identity, and impurity profiles. Our quality commitment ensures material suitable for demanding R&D and scale-up applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber-colored or stored in light-resistant packaging.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.