Description

Fmoc-Lys(Trt)-Oh is a protected amino acid derivative widely used as a critical building block in solid-phase peptide synthesis (SPPS). This compound is essential for researchers and manufacturers requiring high-purity intermediates to construct complex peptides with precision. It is primarily utilized by the pharmaceutical, biotechnology, and life sciences industries for applications in drug discovery, therapeutic peptide development, and biochemical research.

Application

• Solid-Phase Peptide Synthesis (SPPS): A fundamental building block for the controlled elongation of peptide chains, particularly for incorporating lysine residues with orthogonal side-chain protection.
• Pharmaceutical Intermediates: Serves as a key raw material in the research and development of peptide-based active pharmaceutical ingredients (APIs) and therapeutic candidates.
• Bioconjugation and Labeling: The reactive carboxyl group and protected side chain enable site-specific modifications for creating peptide conjugates, probes, and labeled biomolecules.
• Combinatorial Chemistry Libraries: Used in the generation of diverse peptide libraries for high-throughput screening in drug discovery programs.
• Academic and Industrial Research: A standard reagent in laboratories focused on protein engineering, structural biology, and studying protein-protein interactions.

Basic Information

Product Name	Fmoc-Lys(Trt)-Oh
CAS No.	111061-54-2
Molecular Formula	C46H42N2O4
Molecular Weight	686.84 g/mol
Synonyms	Fmoc-Lys(Trt)-OH; Nα-Fmoc-Nε-trityl-L-lysine; Fmoc-Lys(Trt)-OH; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N6-(triphenylmethyl)-L-lysine; Fmoc-Nε-Trt-L-lysine; Fmoc-Lys(Trt)-OH; Fmoc-Lys(Trt); (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-6-(tritylamino)hexanoic acid
EINECS	Contact for details

Quality Control

Our Fmoc-Lys(Trt)-Oh is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for sensitive applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis for enantiomeric excess, and identity confirmation via spectroscopic methods. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Specific Rotation	-10.0° to -14.0° (c=1 in DMF)
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.