Description

8-Amino-7-(2,3-Dihydroxypropyl)-1,3-Dimethyl-Purine-2,6-Dione is a high-purity, specialty xanthine derivative with a unique functionalized side chain. This compound serves as a critical advanced intermediate in the synthesis of complex pharmaceutical agents, particularly those targeting neurological and cardiovascular pathways. It is essential for research and development chemists and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors who require reliable, high-quality building blocks for API development.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel adenosine receptor antagonists and other purine-based active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a standard or reagent in enzymatic studies and metabolic pathway research related to purine metabolism.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of complex molecules for agrochemicals and other specialty chemicals.
• Reference Standard: Serves as a certified reference material (CRM) for quality control and analytical method development in pharmaceutical laboratories.

Basic Information

Product Name	8-Amino-7-(2,3-Dihydroxypropyl)-1,3-Dimethyl-Purine-2,6-Dione
CAS No.	111038-25-6
Molecular Formula	C₁₁H₁₇N₅O₄
Molecular Weight	283.29 g/mol
Synonyms	8-Amino-1,3-dimethyl-7-(2,3-dihydroxypropyl)-3,7-dihydro-1H-purine-2,6-dione; 8-Amino-7-(2,3-dihydroxypropyl)theophylline; 8-Aminopentoxifylline; 8-APT; 1,3-Dimethyl-8-amino-7-(2,3-dihydroxypropyl)xanthine; HWA 285; BL 191
EINECS	Contact for details

Quality Control

Our 8-Amino-7-(2,3-Dihydroxypropyl)-1,3-Dimethyl-Purine-2,6-Dione is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing including HPLC, NMR, and mass spectrometry to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed and away from direct light to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Total impurities ≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.