Description

Tyrosyl-Seryl(o-T-Butyl)-Glycyl-Phenylalanyl-Leucyl-Threonine(o-T-Butyl) is a protected hexapeptide sequence of significant interest in advanced pharmaceutical research and development. This compound serves as a critical synthetic intermediate, enabling the controlled construction of complex peptide-based therapeutics and bioactive molecules. It is primarily utilized by research institutions, biotechnology firms, and pharmaceutical companies engaged in drug discovery, particularly for metabolic and hormonal disorder research.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel peptide drugs and hormone analogs.
• Drug Discovery Research: Used in structure-activity relationship (SAR) studies to develop new therapeutic candidates.
• Bioconjugation: Serves as a linker or spacer molecule in the development of peptide-drug conjugates (PDCs).
• Biochemical Research: A tool compound for studying enzyme-substrate interactions and peptide metabolism.
• Custom Peptide Synthesis: A critical raw material for contract research and manufacturing organizations (CROs/CMOs) producing custom peptides.
• Reference Standard: Can be qualified for use as a high-purity analytical reference standard in quality control laboratories.

Basic Information

Product Name	Tyrosyl-Seryl(o-T-Butyl)-Glycyl-Phenylalanyl-Leucyl-Threonine(o-T-Butyl)
CAS No.	111035-57-5
Molecular Formula	C46H68N8O12
Molecular Weight	925.08 g/mol
Synonyms	Tyr-Ser(tBu)-Gly-Phe-Leu-Thr(tBu); H-Tyr-Ser(tBu)-Gly-Phe-Leu-Thr(tBu)-OH; Y-S(tBu)-G-F-L-T(tBu); Hexapeptide YS(tBu)GFLT(tBu); N-(N-(N-(N-(N2-[(tert-Butoxy)carbonyl]-O-tert-butyl-L-seryl)glycyl)-L-phenylalanyl)-L-leucyl)-O-tert-butyl-L-threonine; Protected YS(tBu)GFLT(tBu) sequence
EINECS	Contact for details

Quality Control

Our Tyrosyl-Seryl(o-T-Butyl)-Glycyl-Phenylalanyl-Leucyl-Threonine(o-T-Butyl) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, MS for identity confirmation, and chiral analysis to ensure stereochemical integrity. Certificates of Analysis (COA) detailing all specifications are provided to guarantee compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept sealed in a dry environment to prevent moisture uptake, which can affect stability and handling properties. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95.0%
Assay	≥ 97.0% (on anhydrous basis)
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.