Description

3-Quinolinecarboxylic Acid, 5-Amino-1-Cyclopropyl-6,8-Difluoro-1,4-Dihydro-7-(3-Methyl-1-Piperazinyl)-4-Oxo-, Ethyl Ester is a high-purity, complex heterocyclic compound of significant interest in advanced pharmaceutical synthesis. This molecule serves as a critical advanced pharmaceutical intermediate (API intermediate), valued for its specific structural motifs that enable the development of novel therapeutic agents. It is primarily sought by research institutions, contract research organizations (CROs), and pharmaceutical manufacturers engaged in the discovery and production of next-generation antibacterial and antimicrobial drugs.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel fluoroquinolone-class antibiotics and other antimicrobial agents.
• Antibacterial Drug Research: Used in R&D for developing new compounds targeting resistant bacterial strains.
• Chemical Synthesis: Serves as a versatile precursor for creating more complex molecular structures in medicinal chemistry.
• Biochemical Research: Employed in studies investigating structure-activity relationships (SAR) of quinolone derivatives.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for cGMP production of active pharmaceutical ingredients (APIs).
• Reference Standard: Utilized as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.

Basic Information

Item	Details
Product Name	3-Quinolinecarboxylic Acid, 5-Amino-1-Cyclopropyl-6,8-Difluoro-1,4-Dihydro-7-(3-Methyl-1-Piperazinyl)-4-Oxo-, Ethyl Ester
CAS No.	110871-98-2
Molecular Formula	C20H24F2N4O3
Molecular Weight	406.43 g/mol
Synonyms	Ethyl 5-Amino-1-cyclopropyl-6,8-difluoro-7-(3-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylate; 5-Amino-1-cyclopropyl-6,8-difluoro-1,4-dihydro-7-(3-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic Acid Ethyl Ester; Gatifloxacin Ethyl Ester; Gatifloxacin Intermediate; AM-1155 Ethyl Ester; GTX Ethyl Ester; Ethyl 1-Cyclopropyl-6,8-difluoro-1,4-dihydro-7-(3-methylpiperazin-1-yl)-4-oxo-5-(amino)-3-quinolinecarboxylate
EINECS	Contact for details

Quality Control

Our production of this pharmaceutical-grade intermediate adheres to stringent quality protocols. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the exacting standards required for pharmaceutical synthesis. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to support regulatory filings. We operate under a cGMP-compliant quality management system to ensure traceability, consistency, and reliability for our global B2B clients.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.