Description

Isoleucyl-Arginyl-Isoleucyl-Cysteinyl-Arginyl-Lysyl-Glycine Ethyl Ester is a synthetic peptide derivative of significant interest in advanced biochemical research and development. This compound matters for its role as a key intermediate or active sequence in the design of novel therapeutic agents and diagnostic tools. It is primarily needed by pharmaceutical R&D laboratories, biotechnology companies, and academic institutions focused on peptide-based drug discovery, enzymology studies, and the development of targeted bioactive molecules.

Application

• Pharmaceutical Research & Development: Serves as a critical building block or reference standard in the synthesis of novel peptide-based drugs and prodrugs.
• Biochemical Assay Development: Used as a substrate, inhibitor, or model compound in enzymatic studies and high-throughput screening assays.
• Proteomics and Signal Transduction Research: Employed to study protein-protein interactions, kinase substrates, or protease activity due to its specific arginine and cysteine-containing sequence.
• Cosmeceutical Ingredient Research: Investigated for potential bioactive properties in advanced skincare formulations targeting specific cellular pathways.
• Diagnostic Reagent Manufacturing: Utilized in the production of specialized reagents for clinical diagnostics and immunological tests.
• Academic & Institutional Research: A valuable tool for universities and research institutes conducting fundamental studies in peptide chemistry and molecular biology.

Basic Information

Product Name	Isoleucyl-Arginyl-Isoleucyl-Cysteinyl-Arginyl-Lysyl-Glycine Ethyl Ester
CAS No.	110786-25-9
Molecular Formula	C37H71N15O9S
Molecular Weight	886.13 g/mol
Synonyms	IRI-CR-KG-OEt; H-Ile-Arg-Ile-Cys-Arg-Lys-Gly-OEt; IRI-CR-KG Ethyl Ester; Isoleucine-Arginine-Isoleucine-Cysteine-Arginine-Lysine-Glycine Ethyl Ester; Peptide IRICRKG Ethyl Ester; (6S,9S,12S,15S,18S,21S)-6,12,15,21-Tetra(3-methylbutyl)-3,9,18-tris(3-guanidinopropyl)-2,5,8,11,14,17,20-heptaoxo-1-oxa-4,7,10,13,16,19-hexaazacyclotricosane-22-carboxylic acid ethyl ester; Ethyl (2S)-2-[[(2S)-2-[[(2S)-2-[[(2R)-2-[[(2S)-2-[[(2S)-2-amino-5-guanidino-pentanoyl]amino]-5-guanidino-pentanoyl]amino]-3-sulfanyl-propanoyl]amino]-3-methyl-pentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-4-methyl-pentanoyl]amino]acetate
EINECS	Contact for details

Quality Control

Our Isoleucyl-Arginyl-Isoleucyl-Cysteinyl-Arginyl-Lysyl-Glycine Ethyl Ester is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, MS for identity confirmation, and tests for residual solvents and related substances, to ensure it meets the high standards required for research applications. Certificates of Analysis (COA) with detailed chromatographic data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. Under these conditions, the product is stable for extended periods. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture absorption. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Assay (Peptide Content)	≥ 80.0%
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC/IC)	≤ 10.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.