Description

Carbobenzoxy-Phenylalanyl(P)-Leucyl-Alanine is a synthetic peptide derivative featuring a phosphorylated tyrosine residue, designed for advanced biochemical research. This compound serves as a crucial tool for studying enzyme kinetics, signal transduction pathways, and protein-protein interactions. It is primarily utilized by research institutions and pharmaceutical companies engaged in proteomics, kinase assay development, and the discovery of novel therapeutic agents.

Application

• Biochemical Research: Used as a specialized substrate or inhibitor in enzymatic studies, particularly for kinases and phosphatases.
• Proteomics & Signal Transduction: A key reagent for investigating phosphorylation-dependent cellular signaling cascades and protein function.
• Pharmaceutical Development: Employed in high-throughput screening (HTS) assays to identify and characterize potential drug candidates targeting specific enzymatic activity.
• Peptide Synthesis Intermediate: Serves as a building block or a protected fragment in the solid-phase or solution-phase synthesis of more complex phosphopeptides.
• Antibody Production & Validation: Can be used as an antigen to generate and validate phospho-specific antibodies for immunodetection applications.

Basic Information

Product Name	Carbobenzoxy-Phenylalanyl(P)-Leucyl-Alanine
CAS No.	110786-00-0
Molecular Formula	C30H40N4O9P
Molecular Weight	631.64 g/mol
Synonyms	Z-Phe(P)-Leu-Ala-OH; Cbz-Phe(PO3H2)-Leu-Ala; N-Carbobenzoxy-O-phospho-L-tyrosyl-L-leucyl-L-alanine; Benzyloxycarbonyl-L-phenylalanyl(P)-L-leucyl-L-alanine; CBZ-Phe(P)-Leu-Ala; Z-Tyr(PO3H2)-Leu-Ala; (S)-2-(((S)-1-((S)-4-((((Benzyloxy)carbonyl)amino)(phosphono)methyl)phenoxy)-1-oxo-4-phenylbutan-2-yl)amino)-4-methyl-1-oxopentan-2-yl)amino)propanoic acid
EINECS	Contact for details

Quality Control

Our Carbobenzoxy-Phenylalanyl(P)-Leucyl-Alanine is manufactured under controlled conditions to ensure high purity and batch-to-batch consistency, suitable for sensitive research applications. Each lot undergoes rigorous analytical testing, including HPLC for purity and MS for identity confirmation. Certificates of Analysis (COA) detailing all specifications are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive); allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Solubility	Soluble in DMSO, DMF; slightly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.