Description

Alloc-Gly-Oh·Dcha is a protected amino acid derivative widely used as a key building block in solid-phase peptide synthesis (SPPS). This compound is essential for researchers and manufacturers requiring high-purity intermediates to ensure the fidelity and yield of complex peptide sequences. It is particularly valuable for the pharmaceutical and biotechnology industries in the development of therapeutic peptides, diagnostic agents, and novel biochemical tools.

Application

• Solid-Phase Peptide Synthesis (SPPS): A fundamental Fmoc/Alloc orthogonal protecting group strategy component for the controlled incorporation of glycine.
• Pharmaceutical Intermediate: Serves as a critical raw material in the synthesis of active pharmaceutical ingredients (APIs) for peptide-based drugs.
• Bioconjugation: Used in the preparation of peptide-protein conjugates for antibody-drug conjugates (ADCs) and other targeted therapies.
• Research & Development: A valuable reagent in academic and industrial R&D labs for exploring new peptide structures and functions.
• Combinatorial Chemistry: Employed in the generation of peptide libraries for high-throughput screening in drug discovery.
• Custom Peptide Production: A standard building block for contract research and manufacturing organizations (CROs/CMOs) offering custom peptide services.

Basic Information

Product Name	Alloc-Gly-Oh·Dcha
CAS No.	110637-40-6
Molecular Formula	C₁₉H₃₄N₂O₄
Molecular Weight	354.49 g/mol
Synonyms	N-Alloxycarbonylglycine Dicyclohexylamine Salt; Alloc-Gly-OH·DCHA; Fmoc-Alloc-Gly-OH (common search alias); Glycine, N-[(2-propen-1-yloxy)carbonyl]-, compd. with N-cyclohexylcyclohexanamine (1:1); Allyloxycarbonylglycine Dicyclohexylammonium Salt; N-Alloc-glycine DCHA salt; Boc/Ddz/Alloc Protected Amino Acid; Peptide Synthesis Building Block
EINECS	Contact for details

Quality Control

Our Alloc-Gly-Oh·Dcha is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and chiral analysis to ensure stereochemical integrity. Certificates of Analysis (COA) with detailed specifications are provided to guarantee compliance with your research or cGMP manufacturing requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥98.5%
Specific Rotation	Contact for details
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.