Description

Insulin, Des-Asn(21)-Cys(20)-Ethylamide(A)- CAS NO 110613-07-5 is a chemically modified insulin analog, specifically engineered for advanced research and development in metabolic studies. This high-purity compound is critical for investigating insulin signaling pathways, receptor binding affinity, and the development of novel therapeutic agents. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and biotechnology companies focused on endocrinology and diabetes research.

Application

• Pharmaceutical Research & Development: Serves as a key reference standard and active pharmaceutical ingredient (API) intermediate in the development of novel insulin analogs and diabetes therapeutics.
• Biochemical Assay Development: Used in the calibration and validation of bioanalytical methods, including ELISA, radioimmunoassay (RIA), and surface plasmon resonance (SPR) for insulin detection.
• Metabolic Pathway Studies: Essential for in vitro and ex vivo studies aimed at understanding insulin's mechanism of action, glucose uptake, and cellular signaling cascades.
• Receptor Binding Studies: Employed to study the kinetics and affinity of insulin binding to its cellular receptor (IR), aiding in structure-activity relationship (SAR) research.
• Quality Control & Standardization: Acts as a certified reference material (CRM) for the quality control and potency testing of commercial insulin products in manufacturing settings.

Basic Information

Product Name	Insulin, Des-Asn(21)-Cys(20)-Ethylamide(A)- CAS NO 110613-07-5
CAS No.	110613-07-5
Molecular Formula	C254H377N65O76S6
Molecular Weight	5807.8 g/mol
Synonyms	Des-Asn(B21)-Cys(B20)-Ethylamide-Insulin; Insulin (Des-Asn21, Cys20 ethylamide); Insulin analog (Des-Asn21, Cys20 ethylamide); B21-Desasparagine-B20-cysteine-ethylamide-insulin; [Des-AsnB21, CysB20 ethylamide]-Insulin; Insulin B-chain(1-30)-peptide ethylamide; A21-Desamido Insulin Ethylamide Derivative
EINECS	Contact for details

Quality Control

Our Insulin, Des-Asn(21)-Cys(20)-Ethylamide(A) is manufactured under strict quality systems suitable for research use. Each batch undergoes comprehensive analytical testing including HPLC for purity and identity confirmation to ensure consistency and reliability. Certificates of Analysis (COA) with detailed chromatographic data are available upon request for traceability and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). For long-term storage, keep desiccated. Allow the vial to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Biological Activity	Assessed by receptor binding assay

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.