Description

Ethyl 6-Methyl-4-(3-Nitrophenyl)-2-Oxo-1,2,3,4-Tetrahydropyrimidine-5-Carboxylate is a high-purity, advanced pharmaceutical intermediate with a defined molecular structure. This compound is a key synthetic precursor in the development of active pharmaceutical ingredients (APIs), particularly those targeting complex therapeutic areas. It is essential for research and manufacturing organizations in the pharmaceutical and fine chemical sectors requiring reliable, high-quality building blocks for drug discovery and process development.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel drug candidates, particularly dihydropyrimidinone (DHPM) derivatives known for their diverse biological activities.
• API Synthesis: Used in the research and production of Active Pharmaceutical Ingredients (APIs) for potential therapeutic applications.
• Medicinal Chemistry Research: Serves as a versatile scaffold in drug discovery programs for creating libraries of compounds for biological screening.
• Fine Chemical Production: Employed in the multi-step synthesis of complex, high-value specialty chemicals.
• Academic & Industrial R&D: A valuable reagent for universities and corporate R&D labs studying heterocyclic chemistry and reaction methodologies.

Basic Information

Product Name	Ethyl 6-Methyl-4-(3-Nitrophenyl)-2-Oxo-1,2,3,4-Tetrahydropyrimidine-5-Carboxylate
CAS No.	110448-29-8
Molecular Formula	C15H15N3O5
Molecular Weight	317.30 g/mol
Synonyms	Ethyl 4-(3-Nitrophenyl)-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate; 4-(3-Nitrophenyl)-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylic acid ethyl ester; 5-Carbethoxy-4-(3-nitrophenyl)-6-methyl-3,4-dihydropyrimidin-2(1H)-one; 3,4-Dihydropyrimidin-2(1H)-one, 5-(ethoxycarbonyl)-4-(3-nitrophenyl)-6-methyl-; Biginelli Reaction Product; DHPM Derivative
EINECS	Contact for details

Quality Control

Our Ethyl 6-Methyl-4-(3-Nitrophenyl)-2-Oxo-1,2,3,4-Tetrahydropyrimidine-5-Carboxylate is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming the product meets agreed specifications for pharmaceutical intermediate applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.