Description

3-(2-Hydroxyethyl)-6,7-Dimethoxyquinazoline-2,4(1H,3H)-Dione is a high-purity quinazoline derivative, a crucial advanced pharmaceutical intermediate for the synthesis of complex active pharmaceutical ingredients (APIs). Its value lies in providing a functionalized scaffold that enables the development of novel therapeutic agents, particularly in oncology and central nervous system (CNS) research. This compound is essential for R&D laboratories, process development chemists, and manufacturers in the pharmaceutical and fine chemical industries seeking reliable, high-quality building blocks for drug discovery and production.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug molecules, particularly those targeting specific enzyme pathways.
• Oncology Research: Used in the development of novel kinase inhibitors and other targeted cancer therapies due to the quinazoline core structure.
• CNS Drug Development: Serves as a precursor for compounds being investigated for neurological and psychiatric disorders.
• Process Chemistry & Scale-up: Employed in route scouting and optimization for the commercial manufacturing of APIs.
• Biochemical Research: Utilized as a reference standard or a probe in biochemical assays to study protein-ligand interactions.
• Custom Synthesis: Acts as a starting material for the custom synthesis of specialized derivatives for client-specific research programs.

Basic Information

Product Name	3-(2-Hydroxyethyl)-6,7-Dimethoxyquinazoline-2,4(1H,3H)-Dione
CAS No.	110231-25-9
Molecular Formula	C₁₂H₁₄N₂O₅
Molecular Weight	266.25 g/mol
Synonyms	6,7-Dimethoxy-3-(2-hydroxyethyl)quinazoline-2,4(1H,3H)-dione; 3-(2-Hydroxyethyl)-6,7-dimethoxy-1H,3H-quinazoline-2,4-dione; 6,7-Dimethoxy-3-(2-hydroxyethyl)-1H,3H-quinazoline-2,4-dione; 2,4(1H,3H)-Quinazolinedione, 3-(2-hydroxyethyl)-6,7-dimethoxy-; 3-(2-Hydroxyethyl)-6,7-dimethoxyquinazoline-2,4-dione
EINECS	Contact for details

Quality Control

Our 3-(2-Hydroxyethyl)-6,7-Dimethoxyquinazoline-2,4(1H,3H)-Dione is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for pharmaceutical R&D and production. A comprehensive Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.