Description

[2-(Pentafluorophenoxy)Ethyl]Amine Hydrochloride is a high-purity, specialized organic salt featuring a pentafluorophenoxy moiety, making it a valuable fluorinated building block for advanced chemical synthesis. Its primary value lies in enabling the introduction of both an amine handle and a highly electron-deficient aromatic system into target molecules, which is critical for modulating physicochemical properties. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries who require precise fluorination to develop new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in drug discovery programs targeting CNS disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides where the pentafluorophenyl group enhances bioavailability and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis and organocatalysis.
• Polymer and Material Science: Incorporated into monomers for the production of high-performance, fluorinated polymers with unique surface properties and chemical resistance.
• Bioconjugation and Probe Synthesis: Utilized in the preparation of fluorescent probes, affinity labels, and other biochemical tools for life science research.
• Custom Synthesis and R&D: A critical starting material for contract research organizations (CROs) and fine chemical companies engaged in custom synthesis projects.

Basic Information

Product Name	[2-(Pentafluorophenoxy)Ethyl]Amine Hydrochloride
CAS No.	110225-28-0
Molecular Formula	C8H7ClF5NO
Molecular Weight	263.59 g/mol
Synonyms	2-(Pentafluorophenoxy)ethanamine hydrochloride; 2-(Pentafluorophenoxy)ethylamine HCl; Ethanamine, 2-(pentafluorophenoxy)-, hydrochloride; 2-Aminoethyl pentafluorophenyl ether hydrochloride; Pentafluorophenoxyethylamine hydrochloride; 110225-28-0; 2-(Perfluorophenoxy)ethylamine hydrochloride
EINECS	Contact for details

Quality Control

Every batch of [2-(Pentafluorophenoxy)Ethyl]Amine Hydrochloride is manufactured under strict quality management systems. We employ advanced analytical techniques including HPLC, NMR, and MS to ensure identity, purity, and consistency meet the exacting standards required for research and commercial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.