Description

Angiotensinogen (1-14) (Rat) is a specific peptide fragment derived from rat angiotensinogen, a key precursor in the renin-angiotensin system (RAS). This compound is essential for biochemical research focused on hypertension, cardiovascular disease, and renal function. It is primarily used by researchers and manufacturers in pharmaceutical R&D, academic laboratories, and diagnostic development for studying enzyme kinetics, receptor binding, and developing novel therapeutic agents.

Application

• Biochemical Research: Used as a specific substrate for studying renin activity and the initial steps of the angiotensin cascade.
• Pharmaceutical Development: Serves as a critical reference standard and tool compound in the discovery of drugs targeting hypertension and heart failure.
• Enzyme Assay Development: Employed in the development and validation of in vitro diagnostic and high-throughput screening assays.
• Academic Studies: Facilitates fundamental research into the molecular mechanisms of the Renin-Angiotensin-Aldosterone System (RAAS) in rodent models.
• Peptide Chemistry: Acts as a building block or reference material for synthetic peptide chemistry and structure-activity relationship (SAR) studies.

Basic Information

Product Name	Angiotensinogen (1-14) (Rat)
CAS No.	110200-37-8
Molecular Formula	C71H111N21O20S
Molecular Weight	1570.8 g/mol
Synonyms	Rat Angiotensinogen (1-14); Asp-Arg-Val-Tyr-Ile-His-Pro-Phe-His-Leu-Leu-Val-Tyr-Ser (Rat); Angiotensinogen Fragment 1-14 (Rat); Angiotensin I Precursor (1-14), Rat; DRVYIHPFHLLVYS; DRVYIHPFHLLVYS-OH; Angiotensinogen Substrate (Rat); Renin Substrate (Rat)
EINECS	Contact for details

Quality Control

Our Angiotensinogen (1-14) (Rat) is produced under stringent conditions to ensure batch-to-batch consistency and high biological activity. Each lot undergoes comprehensive analytical testing, including HPLC for purity verification and mass spectrometry for identity confirmation. Certificates of Analysis (COA) detailing purity, peptide content, and analytical data are provided to support your research and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by weight)
Amino Acid Analysis	± 10% of theoretical
Water Content (KF)	≤ 5.0%
Solubility	Soluble in water or dilute acetic acid

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.