Description

1-Methyl-D-Tryptophan is a high-purity, non-proteinogenic amino acid derivative of significant interest in advanced biochemical research and pharmaceutical development. Its unique stereochemistry and methyl modification make it a valuable chiral building block and a potential intermediate for novel therapeutic agents. This compound is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors who require precise molecular tools for drug discovery, metabolic studies, and the synthesis of specialized peptides.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of new drug candidates, particularly in oncology and neurology.
• Biochemical Research: Used as a standard, inhibitor, or substrate in enzymatic studies and metabolic pathway investigations related to tryptophan metabolism.
• Peptide Synthesis: Acts as a specialized, modified amino acid residue for the synthesis of novel peptides with enhanced stability or specific biological activity.
• Reference Standard: Employed as a high-purity analytical standard in quality control laboratories for method development and validation.
• Enzyme Inhibition Studies: Investigated for its potential role as an inhibitor for specific enzymes like indoleamine 2,3-dioxygenase (IDO).
• Academic & Institutional Research: Supports fundamental research in medicinal chemistry, chemical biology, and structural biology at universities and research institutes.

Basic Information

Item	Detail
Product Name	1-Methyl-D-Tryptophan
CAS No.	110117-83-4
Molecular Formula	C12H14N2O2
Molecular Weight	218.25 g/mol
Synonyms	D-1-Methyltryptophan; (R)-1-Methyltryptophan; NSC 721782; 1-Methyl-D-trp; D-1-MT; (2R)-2-Amino-3-(1-methyl-1H-indol-3-yl)propanoic acid; 1-Methyl-(R)-tryptophan; Indoximod (common research name)
EINECS	Contact for details

Quality Control

Our 1-Methyl-D-Tryptophan is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry guidelines to support our clients' regulatory and compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Optical Rotation	Contact for details
Loss on Drying	≤1.0%
Heavy Metals	≤20 ppm
Residue on Ignition	≤0.1%
Related Substances (HPLC)	Individual impurity ≤0.5%; Total impurities ≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.