Description

Ethanone, 1-(2-Chloro-5-Pyrimidinyl)- (9Ci) is a high-purity organic intermediate featuring a chloropyrimidine core, a privileged scaffold in medicinal chemistry. This compound is critical for the synthesis of advanced pharmaceutical ingredients and agrochemicals, offering a versatile building block for nucleophilic aromatic substitution and cross-coupling reactions. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries to develop novel active compounds.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of kinase inhibitors, antiviral agents, and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and plant growth regulators.
• Material Science Research: Serves as a precursor for functionalized pyrimidine-based ligands, polymers, and organic electronic materials.
• Chemical Biology: Employed in the development of molecular probes and biochemical tools for target identification and validation.
• Custom Synthesis & Contract Manufacturing: A critical starting material for CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for client projects.

Basic Information

Product Name	Ethanone, 1-(2-Chloro-5-Pyrimidinyl)- (9Ci)
CAS No.	110100-00-0
Molecular Formula	C6H5ClN2O
Molecular Weight	156.57 g/mol
Synonyms	1-(2-Chloro-5-pyrimidinyl)ethanone; 2-Chloro-5-acetylpyrimidine; 2'-Chloro-5'-acetylpyrimidine; 1-(2-Chloro-5-pyrimidinyl)ethan-1-one; 2-Chloro-5-pyrimidinyl methyl ketone; 5-Acetyl-2-chloropyrimidine; Ethanone, 1-(2-chloro-5-pyrimidinyl)-
EINECS	Contact for details

Quality Control

Our Ethanone, 1-(2-Chloro-5-Pyrimidinyl)- (9Ci) is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment supports compliance with cGMP, ISO, and other relevant regulatory frameworks for pharmaceutical and industrial applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed and away from direct light to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.