Description

2,4(1H,3H)-Pyrimidinedione, 1-(Chloroacetyl)-5-Fluoro- (9Ci) is a high-purity fluorinated pyrimidine derivative, serving as a critical building block in advanced organic synthesis. Its molecular structure, featuring both chloroacetyl and fluoro substituents, makes it an essential intermediate for creating complex, biologically active molecules. This compound is primarily required by pharmaceutical R&D and fine chemical manufacturers for the development of novel active pharmaceutical ingredients (APIs) and specialty agrochemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of fluorinated nucleoside analogs and other potential antiviral or anticancer agents.
• Agrochemical Research: Building block for developing new herbicides and pesticides with enhanced activity and selectivity.
• Chemical Synthesis: Versatile reagent for introducing the 1-(chloroacetyl)-5-fluoropyrimidine moiety into more complex molecular architectures.
• Life Science Research: Used in biochemical research as a tool compound to study enzyme inhibition and metabolic pathways.
• Material Science: Potential monomer or precursor for specialty polymers and advanced organic materials.

Basic Information

Product Name	2,4(1H,3H)-Pyrimidinedione, 1-(Chloroacetyl)-5-Fluoro- (9Ci)
CAS No.	110073-43-3
Molecular Formula	C6H4ClFN2O3
Molecular Weight	206.56 g/mol
Synonyms	1-(Chloroacetyl)-5-fluorouracil; 5-Fluoro-1-(chloroacetyl)uracil; 1-Chloroacetyl-5-fluorouracil; 5-Fluoro-1-chloroacetyluracil; 1-(Chloroacetyl)-5-fluoro-2,4(1H,3H)-pyrimidinedione; 5-Fluoro-1-(2-chloroacetyl)uracil; 2,4-Dihydroxy-5-fluoro-1-(chloroacetyl)pyrimidine; 1-(2-Chloroacetyl)-5-fluorouracil
EINECS	Contact for details

Quality Control

Our production of 2,4(1H,3H)-Pyrimidinedione, 1-(Chloroacetyl)-5-Fluoro- (9Ci) adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced techniques including HPLC, NMR, and MS to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We operate under a quality system designed to meet the standards required for pharmaceutical intermediate applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.