Description

5-Methyl-6-Phenyl-2-Sulfanylidene-1,2,3,4-Tetrahydropyrimidin-4-One is a high-purity, specialized heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key precursor in the development of novel pharmacologically active molecules, particularly within medicinal chemistry research. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to create new compounds with targeted biological activities.

Application

• Pharmaceutical Intermediate: Serves as a critical scaffold for the synthesis of potential drug candidates, including kinase inhibitors and other enzyme-targeted therapeutics.
• Medicinal Chemistry Research: Used extensively in hit-to-lead optimization and structure-activity relationship (SAR) studies to explore new chemical entities.
• Agrochemical Development: Acts as a building block for creating novel active ingredients for crop protection products.
• Fine Chemical Synthesis: Employed in the custom synthesis of complex, high-value specialty chemicals for various industrial applications.
• Academic Research: Utilized in universities and research institutes for studying heterocyclic chemistry reactions and developing new synthetic methodologies.
• Bioconjugation & Probe Development: Potential use in creating chemical probes or tagged molecules for biochemical and diagnostic research due to its reactive thione group.

Basic Information

Product Name	5-Methyl-6-Phenyl-2-Sulfanylidene-1,2,3,4-Tetrahydropyrimidin-4-One
CAS No.	109942-16-7
Molecular Formula	C11H10N2OS
Molecular Weight	218.27 g/mol
Synonyms	5-Methyl-6-phenyl-2-thioxo-1,2,3,4-tetrahydropyrimidin-4-one; 4(3H)-Pyrimidinone, 5-methyl-6-phenyl-2-thioxo-1,2,3,4-tetrahydro-; 2-Thioxo-5-methyl-6-phenyl-1,2,3,4-tetrahydropyrimidin-4-one; 5-Methyl-6-phenyl-2-mercapto-3,4-dihydropyrimidin-4-one; DHPM-thione derivative; Tetrahydropyrimidine-4-one thione
EINECS	Contact for details

Quality Control

Our 5-Methyl-6-Phenyl-2-Sulfanylidene-1,2,3,4-Tetrahydropyrimidin-4-One is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay (HPLC), related substances, and residual solvents. Our quality commitment supports cGMP and ISO standards for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents. For long-term storage, consider an inert atmosphere to maximize stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.