Description

D-Isovaline, 4-Hydroxy- (9Ci) is a specialized non-proteinogenic amino acid derivative, distinguished by its unique stereochemistry and hydroxyl functional group. This compound is valued for its role as a high-purity chiral building block and research standard in advanced organic synthesis and biochemical studies. It is primarily utilized by pharmaceutical R&D teams, academic researchers, and fine chemical manufacturers focused on developing novel peptides, bioactive molecules, and chiral catalysts.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of novel therapeutic agents, particularly in peptide-based drug discovery.
• Biochemical Research: Used as a reference standard or substrate in enzymatic studies and metabolic pathway investigations due to its specific stereochemistry.
• Asymmetric Synthesis: Acts as a chiral auxiliary or ligand precursor in catalytic systems for the synthesis of enantiomerically pure compounds.
• Peptide Modification: Incorporated into custom peptides to study structure-activity relationships (SAR) and to impart specific physicochemical properties.
• Academic & Industrial R&D: Employed in fundamental chemical research exploring the properties and reactivity of unnatural amino acids.
• Fine Chemical Production: Utilized in the multi-step synthesis of complex, high-value specialty chemicals for various industrial applications.

Basic Information

Product Name	D-Isovaline, 4-Hydroxy- (9Ci)
CAS No.	109918-65-2
Molecular Formula	C5H11NO3
Molecular Weight	133.15 g/mol
Synonyms	4-Hydroxy-D-isovaline; (2R)-2-Amino-2-methyl-3-hydroxybutanoic acid; D-4-Hydroxyisovaline; (R)-2-Amino-2-methyl-3-hydroxybutyric acid; 4-Hydroxy-D-isovaline (9CI); D-α-Amino-β-hydroxyisovaleric acid; (2R)-2-Amino-3-hydroxy-2-methylbutanoic acid
EINECS	Contact for details

Quality Control

Our D-Isovaline, 4-Hydroxy- (9Ci) is produced under stringent quality management systems to ensure batch-to-batch consistency and high purity, suitable for research and development applications. We provide comprehensive analytical documentation, including detailed Certificates of Analysis (COA) with results from HPLC, chiral analysis, and NMR spectroscopy. Specifications are designed to meet the rigorous demands of pharmaceutical and fine chemical industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed in a dry environment to prevent product degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.