Description

1,3-Dimethyl-5-(2-Phenylethynyl)-2,4(1H,3H)-Pyrimidinedione is a specialized heterocyclic organic compound featuring a pyrimidinedione core functionalized with a phenylethynyl group. This unique structure makes it a valuable advanced pharmaceutical intermediate and a versatile building block for organic synthesis. It is primarily utilized by pharmaceutical R&D and fine chemical manufacturers for the development of novel active ingredients and complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, particularly for central nervous system (CNS) and antiviral applications.
• Organic Synthesis Building Block: Used in cross-coupling reactions (e.g., Sonogashira) and cyclization processes to construct complex heterocyclic systems.
• Agrochemical Research: Serves as a core structure for developing new active ingredients in crop protection research.
• Material Science: Potential monomer or precursor for specialty polymers and advanced organic electronic materials.
• Academic & Industrial R&D: Used in medicinal chemistry programs for structure-activity relationship (SAR) studies and library synthesis.

Basic Information

Item	Details
Product Name	1,3-Dimethyl-5-(2-Phenylethynyl)-2,4(1H,3H)-Pyrimidinedione
CAS No.	109856-23-7
Molecular Formula	C₁₄H₁₂N₂O₂
Molecular Weight	240.26 g/mol
Synonyms	5-(2-Phenylethynyl)-1,3-dimethylpyrimidine-2,4(1H,3H)-dione; 1,3-Dimethyl-5-(phenylethynyl)uracil; 5-(Phenylethynyl)-1,3-dimethyluracil; DMEPU; 1,3-Dimethyl-5-(2-phenylethynyl)uracil; 5-(2-Phenylethynyl)-1,3-dimethyl-2,4-pyrimidinedione
EINECS	Contact for details

Quality Control

Our production of 1,3-Dimethyl-5-(2-Phenylethynyl)-2,4(1H,3H)-Pyrimidinedione adheres to a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure high chemical integrity and batch-to-batch consistency. Certificates of Analysis (COA) with detailed specifications are provided and can be tailored to meet specific customer requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.