Description

Prolyl-Leucyl-Psi(Methylamino)Glycinamide is a specialized synthetic peptide derivative of significant interest in advanced biochemical research and development. This compound serves as a critical building block and research tool for studying peptide structure-activity relationships and enzyme interactions. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and biotechnology companies focused on novel therapeutic discovery and proteomics. The precise molecular architecture of this peptide makes it valuable for investigating metabolic pathways and developing targeted bioactive molecules.

Application

• Pharmaceutical Research & Development: As a key intermediate or reference standard in the discovery and synthesis of novel peptide-based therapeutics and enzyme inhibitors.
• Biochemical Assay Development: Used as a substrate or modulator in enzymatic studies to investigate protease specificity and catalytic mechanisms.
• Proteomics and Metabolic Pathway Analysis: Employed as a molecular probe to study protein-protein interactions and signal transduction pathways within cells.
• Academic Research: Serves as a valuable compound for university laboratories conducting fundamental research in peptide chemistry, medicinal chemistry, and structural biology.
• Biotechnology Applications: Potential use in the development of diagnostic reagents, biosensors, or affinity purification ligands due to its specific binding characteristics.
• Chemical Biology Tool: Acts as a precursor for synthesizing more complex, labeled, or modified peptides for advanced cellular and molecular studies.

Basic Information

Product Name	Prolyl-Leucyl-Psi(Methylamino)Glycinamide
CAS No.	109772-52-3
Molecular Formula	C17H31N5O4
Molecular Weight	369.46 g/mol
Synonyms	Pro-Leu-ψ[CH2NH]Gly-NH2; Pseudo-peptide Pro-Leu-Gly-NH2 derivative; (S)-1-((S)-2-((S)-1-((S)-2-Amino-1-hydroxyethylamino)-4-methyl-1-oxopentan-2-yl)pyrrolidine-1-carbonyl)-2-methylpropylcarbamic acid; Prolyl-leucyl-glycinamide psi-methylamino analog; Reduced peptide bond Pro-Leu-Gly-NH2; PLG ψ[CH2NH] amide; Allosteric modulator research compound
EINECS	Contact for details

Quality Control

Our Prolyl-Leucyl-Psi(Methylamino)Glycinamide is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for sensitive research applications. Each lot undergoes comprehensive analytical characterization, including HPLC for purity assessment, mass spectrometry for identity confirmation, and chiral analysis to verify stereochemical integrity. Certificates of Analysis (COA) detailing all test results are provided with every shipment. We adhere to cGMP guidelines where applicable for the production of research-grade biochemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment. For long-term storage, consider desiccated conditions. Handle with care to prevent physical damage to the primary container.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.